| Type | Description |
|---|---|
| Definition | lin-28 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:05:00 | reduction in old testis leads to decreased upd levels, hub cell aging, and loss of the stem cell niche | 30713156 |
| 2019-01-19 11:28:00 | Lin-28 does not block the production of let-7 in Drosophila, which suggests the let-7 independent pathway as a molecular mechanism of Lin-28 | 30415010 |
| 2018-07-21 10:33:00 | This FMRP activity is mediated solely via a second conserved RNA-binding protein, LIN-28, known to boost insulin signaling in stem cells. Via LIN-28, FMRP controls progenitor cell behavior by post-transcriptionally repressing the level of insulin receptor (InR). | 29212015 |
| 2016-12-17 12:13:00 | Based on the analyses authors' current view is that LIN-28 is an essential component of an intestinal progenitor-specific ribonucleoprotein (RNP) complex that modulates stem cell division type to adjust tissue growth to dietary conditions. | 26934725 |
| 2016-02-20 10:28:00 | Lin-28 is a stem cell intrinsic factor that boosts insulin signaling in intestinal progenitor cells and promotes their symmetric division in response to nutrients | 26487778 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:RE05342, CG17334, Dmel\CG17334, EP(3)0915, Lin28, lin28 |
| Gene |
UniProtKB-ID:
LIN28_DROME
UniprotKB:
Q9VRN5
UniParc:
UPI0000076E3A
EMBL:
AE014296,
AY118360,
AF521096
EnsemblGenome:
FBgn0035626
KO:
dme:Dmel_CG17334
|
| Nucleutide sequences |
EMBL-CDS:
AAF50758.2,
AAM48389.1,
AAM77748.1
Gene_ORFName:
CG17334
EnsemblGenome_TRS:
FBtr0077090
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0076798
RefSeq:
NP_647983.1
|
| Others |
UniRef100:
UniRef100_Q9VRN5
UniRef90:
UniRef90_Q9VRN5
UniRef50:
UniRef50_Q9VRN5
UniGene:
Dm.13816
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员