| Type | Description |
|---|---|
| Definition | Charged multivesicular body protein 2b |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila. | 32848189 |
| 2019-02-09 12:55:00 | The pro-apoptotic JNK scaffold protein POSH mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia. | 29432529 |
| 2014-03-29 11:46:00 | The results demonstrate that CHMP2B(Intron5) preferentially affects different receptor signaling pathways in a cellular and developmental context-dependent manner. | 24158394 |
| 2014-01-18 11:57:00 | Data show that syntaxin 13 (syx13) is a geneti modifier of the mutant CHMP2B (CHMP2BIntron5) eye phenotype. | 24095276 |
| 2010-01-21 00:00:00 | Spn5 is a regulator of the Toll pathway and CHMP2B (CG4618) toxicity and the Toll pathway is a major signaling pathway misregulated by mutant CHMP2B in vivo. | 19581577 |
| Type | IDs |
|---|---|
| Synonymous | CG4618, Dmel\CG4618, cg4618 |
| Gene |
UniProtKB-ID:
Q9VRJ5_DROME
UniprotKB:
Q9VRJ5
UniParc:
UPI000005E9DC
EMBL:
AY061433,
AE014296
EnsemblGenome:
FBgn0035589
KO:
dme:Dmel_CG4618
|
| Nucleutide sequences |
EMBL-CDS:
AAL28981.1,
AAF50800.1
Gene_ORFName:
Dmel_CG4618,
CG4618
EnsemblGenome_TRS:
FBtr0077166
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0076869
RefSeq:
NP_647947.1
|
| Others |
UniRef100:
UniRef100_Q9VRJ5
UniRef90:
UniRef90_Q9VRJ5
UniRef50:
UniRef50_Q9VRJ5
UniGene:
Dm.850
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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