Type | Description |
---|---|
Definition | keratin 8 |
Date | Results | Publications |
---|---|---|
2021-04-17 13:11:00 | KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis. | 32519739 |
2020-10-31 13:14:00 | Keratin 8 Mutations Were Associated With Susceptibility to Chronic Hepatitis B and Related Progression. | 31515557 |
2020-09-12 16:03:00 | Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. | 32678092 |
2020-06-06 12:28:00 | Using a site-specific mutation assay, we identified K8-Lys108 and K18-Lys187/426 as acetylation sites, and K8-Arg47 and K18-Arg55 as methylation sites. Keratin mutation (Arg-to-Lys/Ala) at the methylation sites, but not the acetylation sites, led to decreased stability of the keratin protein. | 31199680 |
2019-11-30 12:55:00 | Results identified self-antigens, Keratin 8, provoking a self-reactive T cell response suggesting its involvement in the immune-inflammatory mechanism of coronary artery disease. | 30811493 |
Type | IDs |
---|---|
Synonymous | CARD2, CK-8, CK8, CYK8, K2C8, K8, KO |
Gene |
UniProtKB-ID:
K2C8_HUMAN,
Q7L4M3_HUMAN
UniprotKB:
P05787,
Q7L4M3
UniParc:
UPI000006CFE7,
UPI0000161B3E,
UPI0001892789
EMBL:
AK222941,
M34482,
U76549,
X74981,
BC008200,
M26512,
BC063513,
AK290938,
BC075839,
BC073760,
M34225,
X98614,
AK310257,
AC107016,
X74929,
CH471054,
AK315826,
X12882,
BC000654
Ensembl:
ENSG00000170421
KO:
hsa:3856
|
Nucleutide sequences |
EMBL-CDS:
CAA52916.1,
CAA31376.1,
AAA35763.1,
AAH75839.1,
AAA51542.1,
BAF98717.1,
EAW96653.1,
BAF83627.1,
AAA35748.1,
CAA52882.1,
AAH73760.1,
BAD96661.1,
AAH00654.3,
AAB18966.1,
AAH63513.2,
CAA67203.1,
AAH08200.1
Ensembl_TRS:
ENST00000293308,
ENST00000546897,
ENST00000552551,
ENST00000552150
|
Protein sequencees |
Ensembl_PRO:
ENSP00000449404,
ENSP00000447566,
ENSP00000293308,
ENSP00000447402
RefSeq:
NP_001243211.1,
NP_001243222.1,
NP_002264.1
|
Others |
UniRef100:
UniRef100_P05787
UniRef90:
UniRef90_P05787
UniRef50:
UniRef50_P05787
UniGene:
Hs.533782,
Hs.708445
CCDS:
CCDS8841.1,
CCDS58234.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员