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38513 ImpL2

38513

ImpL2

Ecdysone-inducible gene L2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Ecdysone-inducible gene L2

研究结论

Date Results Publications
2019-01-19 11:14:00 beta-sheet fold serves as a direct, high-affinity binder of hormones; likely represents an alternative hormone binding and regulatory IBP system different and evolutionarily independent from human IGFBPs 30242155
2015-06-20 12:59:00 Increased expression of the secreted insulin/IGF antagonist ImpL2 is associated with organ wasting. 25850671
2015-06-20 12:59:00 Increased expression of ImpL2 is associated with cachexia-like wasting. 25850672
2013-11-02 12:02:00 Imp-L2-expressing neurons sense the nutritional state of Drosophila larvae and coordinate dietary information and ecdysone production to adjust developmental timing under starvation conditions 23773803
2011-07-16 10:11:00 role in the longevity 21108726

名称对应

Type IDs
Synonymous CG15009, CT34862, Dmel\CG15009, GH28, IMP-L2, IMPL2, Imp-12, Imp-L2, ImpL-2
Gene
UniProtKB-ID: IMPL2_DROME, M9PEL7_DROME
UniprotKB: Q09024, M9PEL7
UniParc: UPI000034DE2C, UPI0000124695, UPI000034DE2D
EMBL: AE014296, AY060476, BT012299, BT012298, L23066
EnsemblGenome: FBgn0001257
KO: dme:Dmel_CG15009
Nucleutide sequences
EMBL-CDS: AAS77424.1, AAS77423.1, AAL25515.1, AAN11594.2, AAF47866.4, AAN11593.1, AAB59251.1, AGB94104.1
Gene_ORFName: CG15009, Dmel_CG15009, CG15009
EnsemblGenome_TRS: FBtr0333569, FBtr0073250, FBtr0073248, FBtr0073249, FBtr0073249, FBtr0333569
Protein sequencees
EnsemblGenome_PRO: FBpp0305746, FBpp0073105, FBpp0073106, FBpp0073104, FBpp0305746, FBpp0073105
RefSeq: NP_728961.2, NP_728960.1, NP_001261409.1, NP_523921.3
Others
UniRef100: UniRef100_Q09024
UniRef90: UniRef90_Q09024
UniRef50: UniRef50_Q09024
UniGene: Dm.2799

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