Type | Description |
---|---|
Definition | keratin 1 |
Date | Results | Publications |
---|---|---|
2020-12-12 13:26:00 | Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes. | 32179842 |
2020-05-02 12:45:00 | CK-1 SNP and high protein expression levels are associated with vocal leukoplakia and LSCC and promote the transformation from vocal leukoplakia to LSCC in a Chinese Han population. | 31067553 |
2020-01-11 11:44:00 | The Keratin 1-keratin 10-1B knob/pocket mechanism is conserved across keratins and many non-keratin intermediate filaments.Light scattering and circular dichroism measurements demonstrated enhanced aggregation of K1(S233L)/K10-1B in solution without affecting secondary structure. The K1(S233L)/K10-1B octamer structure revealed S233L(K1) causes aberrant hydrophobic interactions between 1B tetramers. | 31036554 |
2019-12-28 12:19:00 | Study reports four unrelated cases (one with sporadic epidermolytic ichthyosis and three with autosomal dominant palmoplantar keratoderma), due to two novel and two recurrent KRT1 mutations. Mutations in KRT1 are not only scattered throughout the keratin 1 protein, as opposed to being clustered, but can result in a range of phenotypes as further confirmed by these mutations, giving a complex genotype/phenotype pattern. | 30288772 |
2019-08-03 12:43:00 | A colon score derived from serum CEA, CA19-9, CK1 and MUC1 is a potential valuable non-invasive index that could be used for detection and screening early stage colon cancer patients | 29734875 |
Type | IDs |
---|---|
Synonymous | CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK |
Gene |
UniProtKB-ID:
K2C1_HUMAN
UniprotKB:
P04264
UniParc:
UPI000013CD4D
EMBL:
M10938,
M98776,
AF237621,
AK313986,
AF304164,
AC055716,
BC063697
Ensembl:
ENSG00000167768
KO:
hsa:3848
|
Nucleutide sequences |
EMBL-CDS:
AAG41947.1,
AAA36153.1,
BAG36698.1,
AAF60327.1,
AAB47721.1,
AAH63697.1
Ensembl_TRS:
ENST00000252244
|
Protein sequencees |
Ensembl_PRO:
ENSP00000252244
RefSeq:
NP_006112.3
|
Others |
UniRef100:
UniRef100_P04264
UniRef90:
UniRef90_P04264
UniRef50:
UniRef50_P04264
UniGene:
Hs.80828
CCDS:
CCDS8836.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员