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3843 IPO5

3843

IPO5

importin 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition importin 5

研究结论

Date Results Publications
2021-04-03 13:28:00 IPO5 promotes malignant progression of esophageal cancer through activating MMP7. 32373960
2020-10-31 13:19:00 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. 32222384
2020-09-26 13:02:00 DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. 31340999
2019-12-21 12:01:00 IPO5 is an oncogene involved in CRC cell proliferation and migration. This highlights the significance of IPO5 in 5-fluorouracil-resistant CRC cells. The oncogenic function of IPO5 was mediated by promoting RAS signalling by increasing the nuclear translocation of RASAL2 31288861
2018-12-01 11:53:00 Results indicate that the interaction between FLIL33 and IPO5 is localized to a specific segment of the FLIL33 protein, is not required for nuclear localization of FLIL33, and protects FLIL33 from proteasome-dependent degradation. 29127199

名称对应

Type IDs
Synonymous IMB3, KPNB3, Pse1, RANBP5, imp5
Gene
UniProtKB-ID: IPO5_HUMAN, B3KWG6_HUMAN, Q9BVS9_HUMAN
UniprotKB: O00410, B3KWG6, Q9BVS9
UniParc: UPI0000D477CA, UPI0000163C1C, UPI00017A8539, UPI0000000DBE, UPI000006DF24
EMBL: AL137120, CH471085, BC000947, AK125031, AL356580, BC045640, BC019309, U72761, BC001497, AK302812, Y08890
Ensembl: ENSG00000065150
KO: hsa:3843
Nucleutide sequences
EMBL-CDS: EAX08980.1, AAH19309.1, CAA70103.1, AAH45640.1, AAH01497.1, AAC51317.1, BAG64012.1, BAG54128.1, AAH00947.1
Ensembl_TRS: ENST00000357602, ENST00000261574, ENST00000651721, ENST00000490680
Protein sequencees
Ensembl_PRO: ENSP00000418393, ENSP00000499125, ENSP00000261574, ENSP00000350219
RefSeq: XP_011519392.1, XP_011519391.1, XP_011519390.1, XP_005254110.1, NP_002262.4, XP_024305114.1, XP_016876051.1, XP_005254109.1, XP_011519389.1
Others
UniRef100: UniRef100_A0A2K5U1B6, UniRef100_O00410
UniRef90: UniRef90_O00410, UniRef90_A0A2K5U1B6
UniRef50: UniRef50_O00410
UniGene: Hs.712598
CCDS: CCDS31999.1

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