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3842 TNPO1

3842

TNPO1

transportin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition transportin 1

研究结论

Date Results Publications
2020-12-12 13:24:00 The Renpenning syndrome-associated protein PQBP1 facilitates the nuclear import of splicing factor TXNL4A through the karyopherin beta2 receptor. 32041777
2020-10-31 13:19:00 Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import. 32161167
2020-02-08 10:48:00 Study provides evidence that TRN-1 mediates the timely release of the HIV-1 genome from the capsid protein shell and efficient viral nuclear import. 31611641
2019-08-03 10:45:00 Transportin 1, a member of the importin-beta family proteins, binds to a PY-NLS(2) sequence motif close to the amino terminus of matrix protein (M1) exposed during acid priming of the viral core. 30692667
2019-02-16 10:51:00 high-affinity binding of karyopherin-beta2 to the FUS C-terminal proline-tyrosine nuclear localization signal tethers the proteins together, allowing multiple, distributed weak intermolecular contacts to disrupt FUS self-association, blocking liquid-liquid phase separation 29677513

名称对应

Type IDs
Synonymous IPO2, KPNB2, MIP, MIP1, TRN
Gene
UniProtKB-ID: TNPO1_HUMAN, A0A024RAM0_HUMAN
UniprotKB: Q92973, A0A024RAM0
UniParc: UPI000020CAB6, UPI000000D987, UPI0001AE73F6
EMBL: U72395, CH471084, BC040340, U70322, U72069, AK301021
Ensembl: ENSG00000083312
KO: hsa:3842
Nucleutide sequences
EMBL-CDS: AAB58254.1, AAC50723.1, AAB68948.1, AAH40340.1, BAG62638.1, EAW95714.1, EAW95713.1
Gene_ORFName: hCG_2015745
Ensembl_TRS: ENST00000523768, ENST00000506351, ENST00000337273
Protein sequencees
Ensembl_PRO: ENSP00000336712, ENSP00000428899, ENSP00000425118
RefSeq: XP_005248558.1, NP_001351221.1, NP_002261.3, NP_001351222.1, NP_001351224.1, NP_694858.1, NP_001351225.1, NP_001351223.1
Others
UniRef100: UniRef100_Q92973
UniRef90: UniRef90_Q92973
UniRef50: UniRef50_Q92973
UniGene: Hs.482497
CCDS: CCDS4016.1, CCDS43329.1

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