| Type | Description |
|---|---|
| Definition | karyopherin subunit alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | Antivirals that target the host IMPalpha/beta1-virus interface. | 33439253 |
| 2018-07-07 12:12:00 | Importin alpha1 is specifically required for the nuclear localization of several important HSV1 proteins, capsid assembly, and capsid egress into the cytoplasm, and may become rate limiting in situ upon infection at low multiplicity or in terminally differentiated cells such as neurons. | 29304174 |
| 2017-11-25 15:40:00 | Karyoppherins constitute integral constituents of the nuclear pore complex whose barrier, transport, and cargo release functionalities establish a continuum under a mechanism of Kap-centric control. | 28864541 |
| 2017-07-08 12:40:00 | Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of induced by IFN-beta, but transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of and induces degradation of cellular Kduanyu15351 via caspase-3. [EV17 = Enterovirus 71] | 28455446 |
| 2016-03-19 11:19:00 | Data show that cytoskeleton associated protein 5 (chTOG) only weakly promotes importin-regulated microtubule nucleation, but acts synergistically with TPX2 protein. | 26414402 |
| Type | IDs |
|---|---|
| Synonymous | IPOA5, NPI-1, RCH2, SRP1 |
| Gene |
UniProtKB-ID:
IMA5_HUMAN,
B3KXZ2_HUMAN
UniprotKB:
P52294,
B3KXZ2
UniParc:
UPI00004A2944,
UPI000013D524
EMBL:
CR456743,
BC003009,
CH471052,
BC002374,
AC083798,
AK299030,
S75295,
AK128280,
AC096861,
BT006959
Ensembl:
ENSG00000114030
KO:
hsa:3836
|
| Nucleutide sequences |
EMBL-CDS:
CAG33024.1,
AAH03009.1,
AAP35605.1,
AAH02374.1,
AAC60648.1,
EAW79482.1,
EAW79483.1,
BAG54654.1,
BAG61106.1
Ensembl_TRS:
ENST00000344337
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343701
RefSeq:
XP_016861853.1,
XP_005247494.1,
XP_024309282.1,
XP_011511097.1,
NP_002255.3,
XP_011511099.1,
XP_016861852.1
|
| Others |
UniRef100:
UniRef100_P52294,
UniRef100_W5QFX7
UniRef90:
UniRef90_P52294
UniRef50:
UniRef50_P52294
UniGene:
Hs.161008
CCDS:
CCDS3013.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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