| Type | Description |
|---|---|
| Definition | PR domain containing 14 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats. | 33637711 |
| 2020-08-15 14:43:00 | the crucial role of Prdm14 in primordial germ cell specification is conserved between rat and mice | 32001439 |
| 2020-06-20 10:03:00 | Authors find that global upregulation of the repressive histone H3 lysine 27 trimethylation (H3K27me3) mark is PRDM14 dosage dependent in PGCs of both sexes. When focusing on XCR, we observed that PRDM14 is required for removal of H3K27me3 from the inactive X-chromosome, which, in contrast to global upregulation, takes place progressively along the PGC migration path. | 31221220 |
| 2020-05-02 12:33:00 | The pluripotency regulator PRDM14 requires the master hematopoietic regulator CBFA2T3 to initiate leukemia in progenitor cells, demonstrating an oncogenic role for CBFA2T3 and providing an avenue for targeting cancer-initiating cells. | 31015254 |
| 2019-09-14 10:43:00 | the co-option of the PRDM14-CBFA2T complex from motor neurons into pluripotent cells may have maintained the transcriptional network for pluripotency during vertebrate evolution. | 30630825 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PRD14_MOUSE
UniprotKB:
E9Q3T6
UniParc:
UPI00001E2DB5
EMBL:
AC091248,
AK141218
Ensembl:
ENSMUSG00000042414
KO:
mmu:383491
|
| Nucleutide sequences |
EMBL-CDS:
BAE24596.1
Ensembl_TRS:
ENSMUST00000047577
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044245
RefSeq:
NP_001074678.2
|
| Others |
UniRef100:
UniRef100_E9Q3T6
UniRef90:
UniRef90_E9Q3T6
UniRef50:
UniRef50_Q9GZV8
UniGene:
Mm.309380
CCDS:
CCDS48221.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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