| Type | Description |
|---|---|
| Definition | kinesin light chain 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein. | 31806024 |
| 2020-04-25 10:36:00 | LMTK2 binds to KLC1 to direct axonal transport of p35 and its loss may contribute to Alzheimer's disease. | 31068217 |
| 2020-01-11 10:41:00 | TGF-beta mediated pro-invasive activity was found to be dependent on KIF5B expression. In contrast, the epithelial differentiation factor and EMT suppressor prolactin (PRL) was found to repress KIF5B gene expression and KIF5B-Snail1 nuclear accumulation, but enhanced KLC1 gene expression and KIF5B-KLC1 interaction. | 31204277 |
| 2019-11-30 10:15:00 | these studies demonstrate that kinesin 1 regulates ciliogenesis through CCDC28B | 29445114 |
| 2019-03-02 12:06:00 | extensive biochemical characterization of the KLC:JIP1 interaction, as well as identification of potential KLC1-binding partners, improves the understanding of how this growing family of cargos is recruited to kinesin1 by KLC1. | 30026235 |
| Type | IDs |
|---|---|
| Synonymous | KLC, KNS2, KNS2A |
| Gene |
UniProtKB-ID:
KLC1_HUMAN,
Q7RTQ2_HUMAN
UniprotKB:
Q07866,
Q7RTQ2
UniParc:
UPI00004081B2,
UPI00002298CC,
UPI00018E181B,
UPI000006D2BC,
UPI00004081AF,
UPI00001D9732,
UPI0000E23AFA,
UPI00002298CD,
UPI00018E181C,
UPI00018E1819,
UPI00018E181A
EMBL:
BK001166,
AF267525,
BC008881,
AY180169,
BK001163,
L04733,
AY180163,
AF267528,
BK000684,
AF267527,
AY180166,
AF267530,
AY180168,
AF267529,
AF267523,
BK000681,
AY180164,
BK001169,
AL139300,
AF267526,
BK001165,
AF267524,
AF267518,
BK001164,
AF267519,
BK000682,
AY180167,
AY180170,
BK001170,
AY180165,
AF267520,
BK001171,
CH471061,
AY244715,
AF267522,
AF267521,
AL049840
Ensembl:
ENSG00000126214
KO:
hsa:3831
|
| Nucleutide sequences |
EMBL-CDS:
AAO62549.1,
AAO64641.1,
DAA01289.1,
DAA01292.1,
AAO62548.1,
DAA01297.1,
EAW81834.1,
AAO62554.1,
DAA01265.1,
DAA01291.1,
AAH08881.1,
AAF72543.1,
AAA16576.1,
AAO62550.1,
AAO62553.1,
DAA01295.1,
DAA01268.1,
AAO62555.1,
AAO62551.1,
DAA01266.1,
DAA01296.1,
AAO62552.1,
DAA01290.1
Ensembl_TRS:
ENST00000347839,
ENST00000334553,
ENST00000553286,
ENST00000348520,
ENST00000634686,
ENST00000554228,
ENST00000557450,
ENST00000452929,
ENST00000246489,
ENST00000389744
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000334618,
ENSP00000341154,
ENSP00000450648,
ENSP00000452487,
ENSP00000414982,
ENSP00000374394,
ENSP00000334523,
ENSP00000450616,
ENSP00000246489,
ENSP00000488938
RefSeq:
NP_001123579.1,
NP_005543.2,
NP_891553.2
|
| Others |
UniRef100:
UniRef100_Q07866,
UniRef100_Q7RTQ2
UniRef90:
UniRef90_Q07866-9,
UniRef90_Q07866
UniRef50:
UniRef50_Q07866-9,
UniRef50_Q07866
UniGene:
Hs.20107,
Hs.657678
CCDS:
CCDS32165.1,
CCDS45168.1,
CCDS41996.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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