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38244 Rap1

38244

Rap1

Rap1 GTPase

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Rap1 GTPase

研究结论

Date Results Publications
2019-11-02 11:19:00 show that Rap1 activity modulates Talin recruitment to sites of adhesion via its direct binding to Talin 30446511
2019-10-26 11:37:00 Rap1, Canoe and Mbt regulated epithelial morphogenesis by coupling stabilization of the adherens junction (AJ) protein E-Cadherin and Bazooka retention at the zonula adherens. 29507112
2019-06-01 12:17:00 the front/back polarity of border cells requires Rap1, hyperactivation of which disrupts cluster polarity and induces misoriented protrusions and loss of asymmetry in the actin network. 29466741
2019-05-18 12:37:00 precisely regulated Rap1 activity reinforces connections between cells and polarizes the cluster, thus facilitating the coordinated collective migration of border cells. 30156466
2018-04-14 11:20:00 Rap1-interacting domains of Canoe mediate adherens junction and tricellular junction recruitment but are dispensable for membrane localization. Data also support a role for Canoe multimerization. These multifactorial inputs shape Canoe localization, correct Bazooka and adherens junction positioning, and thus apical-basal polarity. 29361565

名称对应

Type IDs
Synonymous BEST:GH18528, C-ras3, CG1956, D-Rap1, DRap, DRap1, Dmel\CG1956, Dras3, Dras62B, E(faf), EC3-7, FCG-C, P08645, R, RAP1, Rap, Ras3, RasIII, l(3)62Bf, l(3)R, rap1, ras 3, ras3
Gene
UniProtKB-ID: RAP1_DROME, M9MRT6_DROME
UniprotKB: P08645, M9MRT6
UniParc: UPI00000002D2
EMBL: M80535, AY121688, AF186654, DQ138746, AE014296, X02200
EnsemblGenome: FBgn0004636
KO: dme:Dmel_CG1956
Nucleutide sequences
EMBL-CDS: AAA28845.1, AAF47583.1, CAA26131.1, AAM52015.1, AAF15520.1, ABA86352.1, ADV37460.1, AGB93990.1
Gene_ORFName: CG1956, Dmel_CG1956, CG1956
EnsemblGenome_TRS: FBtr0072867, FBtr0303154, FBtr0332671, FBtr0072867, FBtr0303154, FBtr0332671
Protein sequencees
EnsemblGenome_PRO: FBpp0304917, FBpp0072746, FBpp0292253, FBpp0292253, FBpp0304917, FBpp0072746
RefSeq: NP_476857.1, NP_001189023.1, NP_001261295.1
Others
UniRef100: UniRef100_P08645
UniRef90: UniRef90_P08645
UniRef50: UniRef50_P08645
UniGene: Dm.822

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