| Type | Description |
|---|---|
| Definition | protein arginine N-methyltransferase 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 12:37:00 | Impairment of PRMT8 oligomerization/dimerization by Cterminal deletion induces PRMT8 mis-localization to the mitochondria, prevents the formation of punctate structures by PRMT8(G2A), and inhibits PRMT8(C9S) patch-like plasma membrane localization. | 30670150 |
| 2019-10-19 11:34:00 | Protein arginine methyltransferase 8 (PRMT8) is a cell-type-restricted arginine methyltransferase responsible for proper asymmetric dimethyl arginine level in postmitotic spinal cord motoneurons. PRMT8-dependent arginine methylation is required for neuroprotection against age-related increases of cellular stress. | 30054395 |
| 2017-09-30 11:12:00 | Together, our findings establish important roles for PRMT8 in regulating neuron function and cognition in the mammalian brain. | 28878098 |
| 2017-09-23 12:30:00 | human dermal fibroblast cells express a novel PRMT8 mRNA variant. | 26851891 |
| 2017-07-15 11:22:00 | Prmt8 is involved in synaptic maturation and is a modulator of developmental neuroplasticity. | 27935040 |
| Type | IDs |
|---|---|
| Synonymous | Hrmt1l3, Hrmt1l4 |
| Gene |
UniProtKB-ID:
ANM8_MOUSE
UniprotKB:
Q6PAK3
UniParc:
UPI00001D974C
EMBL:
BK001349,
BC060250,
AC127373
Ensembl:
ENSMUSG00000030350
KO:
mmu:381813
|
| Nucleutide sequences |
EMBL-CDS:
DAA01382.1,
AAH60250.1
Ensembl_TRS:
ENSMUST00000032500
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032500
RefSeq:
XP_006506415.1,
NP_958759.2,
XP_030111350.1
|
| Others |
UniRef100:
UniRef100_Q6PAK3
UniRef90:
UniRef90_Q6PAK3
UniRef50:
UniRef50_Q9NR22
UniGene:
Mm.39750
CCDS:
CCDS57449.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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