| Type | Description |
|---|---|
| Definition | kallikrein related peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:01:00 | Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer. | 32628300 |
| 2020-07-11 11:29:00 | Study report KLK2-FGFR2 fusion protein in 2 unrelated cases of metastatic prostate cancer. Expression of the KLK2-FGFR2 fusion protein in NIH3T3 cells induced a profound morphological change promoting enhanced migration and activation of downstream proteins in FGFR signaling pathways. | 31043681 |
| 2016-05-21 11:12:00 | glycosylation changes the enzymatic activity of KLK2 in a drastically substrate-dependent manner. | 26582203 |
| 2016-02-06 11:49:00 | The results indicated that W-hK2 had a defect in cellular trafficking due to its misfolding and that it activated the unfolded protein response, suggesting a mechanism to explain the association of the T allele with higher prostate cancer risk. | 25847286 |
| 2015-06-06 14:29:00 | miR-378 was predicted to target both KLK2 and KLK4 and downregulated levels detected in prostate cancer patients. | 25153390 |
| Type | IDs |
|---|---|
| Synonymous | KLK2A2, hGK-1, hK2 |
| Gene |
UniProtKB-ID:
KLK2_HUMAN,
B4DU77_HUMAN,
A0A024R4N3_HUMAN,
A0A024R4J4_HUMAN
UniprotKB:
P20151,
B4DU77,
A0A024R4N3,
A0A024R4J4
UniParc:
UPI000206529C,
UPI00017A7D75,
UPI000002ACDA,
UPI0000169A48,
UPI000004CA0C
EMBL:
AK300566,
M18157,
AF243527,
AC037199,
LT631552,
AK300549,
AF188747,
BT006650,
BC005196,
AK300527,
CH471135,
M18156,
AF188745,
S39329,
AF188746
Ensembl:
ENSG00000167751
KO:
hsa:3817
|
| Nucleutide sequences |
EMBL-CDS:
AAF08277.1,
AAA74454.1,
AAH05196.1,
BAG62272.1,
AAF08276.1,
AAD13817.1,
AAD13816.1,
AAP35296.1,
BAG62255.1,
AAF08275.1,
AAG33356.1,
BAG62239.1,
EAW71939.1,
EAW71938.1,
EAW71937.1,
SFW93199.1,
EAW71940.1
Gene_ORFName:
hCG_22932,
hCG_22932
Ensembl_TRS:
ENST00000597439,
ENST00000391810,
ENST00000325321,
ENST00000358049
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000471214,
ENSP00000375686,
ENSP00000313581,
ENSP00000350748
RefSeq:
NP_001243009.1,
NP_001002231.1,
NP_005542.1
|
| Others |
UniRef100:
UniRef100_P20151,
UniRef100_A0A024R4N3,
UniRef100_B4DU77
UniRef90:
UniRef90_H2NZU0,
UniRef90_P20151
UniRef50:
UniRef50_H2NZU0,
UniRef50_P20151
UniGene:
Hs.515560
CCDS:
CCDS42597.1,
CCDS58675.1,
CCDS12808.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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