Xkr8 - X-linked Kx blood group related 8-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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381560 Xkr8

基因描述

Type	Description
Definition	X-linked Kx blood group related 8

研究结论

Date	Results	Publications
2020-04-11 12:41:00	Xkr8 (-/-) male mice were infertile due to reduced sperm counts in their epididymides.	31712393
2019-05-04 11:48:00	These results indicate that PtdSer exposure can be increased by the phosphorylation-mediated activation of Xkr8 scramblase and flippase down-regulation.	30718401
2018-08-04 12:16:00	These results indicate that the Xkr8-mediated PtdSer exposure in apoptotic lymphocytes and aged neutrophils is essential for their clearance, and its defect activates the immune system, leading to lupus-like autoimmune disease.	29440417
2017-11-25 15:28:00	The Xkr8 influences myogenesis by acting as a positive regulator of terminal differentiation and myoblast survival.	28881496
2015-01-03 11:36:00	Unlike Xkr8, which is ubiquitously expressed, Xkr4 and Xkr9 expression is tissue-specific.	25231987

名称对应

Type	IDs
Synonymous	4931440N07Rik, AI597014, Gm1031, XRG8, mXkr8
Gene	UniProtKB-ID: XKR8_MOUSE UniprotKB: Q8C0T0 UniParc: UPI00000EA280 EMBL: AL627130, BC057035, AY534254, AK029920, CH466552 Ensembl: ENSMUSG00000037752 KO: mmu:381560
Nucleutide sequences	EMBL-CDS: EDL30093.1, BAC26677.1, AAH57035.1, AAT07103.1 Ensembl_TRS: ENSMUST00000045550
Protein sequencees	Ensembl_PRO: ENSMUSP00000041205 RefSeq: XP_006539052.1, NP_958756.1, XP_006539051.1
Others	UniRef100: UniRef100_Q8C0T0 UniRef90: UniRef90_Q8C0T0 UniRef50: UniRef50_Q8C0T0 UniGene: Mm.44558 CCDS: CCDS18732.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
31712393	Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice. Mol Cell Biol Yahiro Yamashita , Chigure Suzuki , Yasuo Uchiyama , Shigekazu Nagata	2020-01-16	-
30718401	Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure. Proc. Natl. Acad. Sci. U.S.A. Takaharu Sakuragi , Hidetaka Kosako , Shigekazu Nagata	2019-02-19	-
29440417	Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase. Proc. Natl. Acad. Sci. U.S.A. Mahiru Kawano , Shigekazu Nagata	2018-02-27	-
30559640	Xkr8 Modulates Bipolar Cell Number in the Mouse Retina. Front Neurosci Amanda G Kautzman , Patrick W Keeley , Caroline R Ackley , Stephanie Leong , Irene E Whitney , Benjamin E Reese	2018-01-01	-
28881496	Xk-related protein 8 regulates myoblast differentiation and survival. FEBS J. Go-Woon Kim , Gi-Hoon Nam , In-San Kim , Seung-Yoon Park	2017-09-07	-
25231987	Exposure of phosphatidylserine by Xk-related protein family members during apoptosis. J Biol Chem Jun Suzuki , Eiichi Imanishi , Shigekazu Nagata	2014-10-31	-
23845944	Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science Jun Suzuki , Daniel P Denning , Eiichi Imanishi , H Robert Horvitz , Shigekazu Nagata	2013-07-26	Xkr8, ced-8, XKR8
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735

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