| Type | Description |
|---|---|
| Definition | RING CCCH (C3H) domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:02:00 | Roquin-1 Regulates Macrophage Immune Response and Participates in Hepatic | 31996460 |
| 2020-01-18 10:11:00 | In mice, loss of post-transcriptional regulation by Roquin-1 results in increased expression of ICOS and Ox40 in T cells. In the absence of Roquin-1, mice develop an immunopathology characterized by the expansion of effector T cells and Tregs, monocytosis and eosinophilia. | 31636267 |
| 2019-07-20 12:09:00 | analysis of previously unknown cis-regulatory elements in Roquin protein | 30295819 |
| 2019-01-12 10:18:00 | most Roquin targets are regulated by mRNA decay, whereas a small subset, including the Nfat5 mRNA, with more binding sites in their 3'-UTRs, are also subject to translational inhibition. | 30232334 |
| 2018-02-24 10:30:00 | Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. | 29352114 |
| Type | IDs |
|---|---|
| Synonymous | 5730557L09Rik, Gm551, N28103, mKIAA2025 |
| Gene |
UniProtKB-ID:
RC3H1_MOUSE
UniprotKB:
Q4VGL6
UniParc:
UPI000047600E
EMBL:
BC138663,
AK173335,
AY948287
Ensembl:
ENSMUSG00000040423
KO:
mmu:381305
|
| Nucleutide sequences |
EMBL-CDS:
AAY16368.1,
BAD32613.1,
AAI38664.1
Ensembl_TRS:
ENSMUST00000161609
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124871
RefSeq:
NP_001020123.1
|
| Others |
UniRef100:
UniRef100_Q4VGL6
UniRef90:
UniRef90_Q4VGL6
UniRef50:
UniRef50_Q4VGL6
UniGene:
Mm.329667
CCDS:
CCDS15410.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员