| Type | Description |
|---|---|
| Definition | presenilin associated, rhomboid-like |
| Date | Results | Publications |
|---|---|---|
| 2014-01-04 12:38:00 | Downregulation of PARL after ischemia is a key step in ischemic neuronal injury, and that it decreases HtrA2 processing and increases neuronal vulnerability. | 23921894 |
| 2013-05-04 10:53:00 | the OPA1/PARL dependent pathway of cristae remodeling is implicated in heat shock. | 22579715 |
| 2010-08-09 11:10:00 | Suppression of PARL protein in healthy myotubes lowered mitochondrial mass and insulin-stimulated glycogen synthesis and increased reactive oxygen species production. | 20444421 |
| 2010-01-21 13:09:00 | results indicate a different function and mechanism of Hax1 in apoptosis and re-opens the question of whether mammalian PARL, in addition to apoptosis, regulates mitochondrial stress response through Omi/HtrA2 processing. | 19680265 |
| 2010-01-21 00:00:00 | Parl-/- mitochondria display reduced levels of OPA1, and OPA1 specifically targeted to IMS complements Parl-/- cells, substantiating the importance of PARL in OPA1 processing.(PARL protein, mouse) | 16839884 |
| Type | IDs |
|---|---|
| Synonymous | D16Ertd607e, PRO2207, PSARL1, PSENIP2, Psarl |
| Gene |
UniProtKB-ID:
PARL_MOUSE
UniprotKB:
Q5XJY4
UniParc:
UPI0000026C48
EMBL:
BC083153,
AK151652
Ensembl:
ENSMUSG00000033918
KO:
mmu:381038
|
| Nucleutide sequences |
EMBL-CDS:
AAH83153.1,
BAE30581.1
Ensembl_TRS:
ENSMUST00000048642
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045361
RefSeq:
NP_001005767.1
|
| Others |
UniRef100:
UniRef100_Q5XJY4
UniRef90:
UniRef90_Q5XJY4
UniRef50:
UniRef50_Q5XJY4
UniGene:
Mm.371737
CCDS:
CCDS28044.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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