| Type | Description |
|---|---|
| Definition | zinc finger and AT hook domain containing |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:23:00 | ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B-H4K8ac-BRD4 axis. | 32997115 |
| 2019-08-10 10:53:00 | Zfat knockdown partially inhibited CD71(-/low)Ter119(-) to CD71(high)Ter119(-) transition of fetal liver erythroid progenitors with impairment in the elevation of CD71 expression. Zfat plays a critical role for erythropoiesis in the fetal liver | 31366551 |
| 2017-07-01 12:42:00 | findings demonstrated that Zfat regulates the transcription of target genes by binding directly to the TSS proximal region, and that Zfat-target genes play important roles in T-cell homeostasis | 27591365 |
| 2017-04-15 10:13:00 | Zfat-deficient T cells show increased numbers of autophagosomes and decreased levels of p62 protein, together indicating that Zfat deficiency promotes lysosomal FoxO1 degradation through autophagy. | 27226588 |
| 2016-01-30 12:07:00 | results demonstrate that Zfat critically participates in the development of DP thymocytes through regulating the activities of p38 and JNK. | 25169027 |
| Type | IDs |
|---|---|
| Synonymous | Gm922, Zfat1, Zfp406 |
| Gene |
UniProtKB-ID:
ZFAT_MOUSE
UniprotKB:
Q7TS63
UniParc:
UPI000171DADE,
UPI00001AAC02
EMBL:
BC053930,
EU221277
Ensembl:
ENSMUSG00000022335
KO:
mmu:380993
|
| Nucleutide sequences |
EMBL-CDS:
AAH53930.1,
ABY67968.1
Ensembl_TRS:
ENSMUST00000160248,
ENSMUST00000162054
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125732,
ENSMUSP00000125257
RefSeq:
XP_006521187.2,
NP_001139360.1,
XP_006521188.2,
XP_030104482.1,
XP_011243985.1,
NP_941046.1
|
| Others |
UniRef100:
UniRef100_Q7TS63
UniRef90:
UniRef90_Q7TS63
UniRef50:
UniRef50_Q7TS63
UniGene:
Mm.309526
CCDS:
CCDS49624.1,
CCDS49623.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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