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380669 Lin28b

380669

Lin28b

lin-28 homolog B (C. elegans)

protein-coding

Mus musculus

基因描述

Type Description
Definition lin-28 homolog B (C. elegans)

研究结论

Date Results Publications
2020-10-31 13:20:00 LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling. 32826333
2020-07-11 11:44:00 A B cell intrinsic switch between positive and negative selection during ontogeny is determined by a change from Lin28b to let-7 gene expression. 32019891
2020-06-13 12:23:00 lin28B is a crucial modulator determining the fate of transplanted mesenchymal stem cells by regulating IGF-2-associated pathways and thereby enhancing their protective effects against AD 31066045
2020-06-06 11:49:00 The Lin28b achieves this by amplifying the CD19/PI3K/c-Myc positive feedback loop, and ectopic Lin28b expression restores both positive selection and mature B cell numbers in CD19(-/-) adult mice. 31562190
2020-05-02 10:21:00 LIP is an inducer of cancer-type metabolic reprogramming and as a regulator of the let-7/LIN28B regulatory circuit 31240246

名称对应

Type IDs
Synonymous 2810403D23Rik, D030047M17Rik, Lin-28.2
Gene
UniProtKB-ID: LN28B_MOUSE
UniprotKB: Q45KJ6
UniParc: UPI00005ABA1C, UPI0000429103, UPI00001C46CB, UPI0000D63356
EMBL: DQ127225, BC089037, AK012973, AC155715, AK133928, AC153847
Ensembl: ENSMUSG00000063804
KO: mmu:380669
Nucleutide sequences
EMBL-CDS: BAE21931.1, AAZ38894.1, BAE43235.1, AAH89037.1
Ensembl_TRS: ENSMUST00000079390
Protein sequencees
Ensembl_PRO: ENSMUSP00000078361
RefSeq: XP_011241487.1, XP_036011766.1, XP_011241482.1, XP_011241490.1, XP_011241488.1, XP_036011767.1, XP_011241489.1, NP_001026942.1, XP_011241485.1, XP_011241484.1
Others
UniRef100: UniRef100_Q45KJ6
UniRef90: UniRef90_Q45KJ6
UniRef50: UniRef50_Q45KJ6
UniGene: Mm.440328
CCDS: CCDS35895.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Harvard Stem Cell Institute

5
2

Johns Hopkins University School of Medicine

3
3

Children's Research Institute

2
4

University of Copenhagen

2
5

Lund University

2
热点人员
排名 研究人员 文献
1

George Q Daley

11
2

P Carninci

7
3

Y Hayashizaki

6
4

Hao Zhu

6
5

H Konno

5
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