| Type | Description |
|---|---|
| Definition | killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:29:00 | matching of KIR2DL1, 2DS1, and 2DS2 in donors with their HLA-C ligands in recipients is associated with increased GvHD, and holds potential for selection of HSCT donors. | 29549293 |
| 2019-02-23 10:42:00 | Higher scores of Childhood Autism Rating Scale (CARS) and Autistic Core Behavior were found in KIR2DS1-C2+/HLA-G *14bp+Autism Spectrum Disorders children (43.7 +/- 1.5, p = 0.03; 3.3 +/- 0.1, p = 0.03, respectively). These results suggested a synergistic polygenic association of KIR2DS1-HLAC2+/HLA-G *14bp+ pattern with behavioral impairment in Autism Spectrum Disorders children. | 28627421 |
| 2018-12-22 11:55:00 | we demonstrated peptide-dependent binding of the activating NK cell receptor KIR2DS1, providing new insights into the underlying mechanisms involved in KIR2DS1-related disorders. | 28546555 |
| 2018-11-10 10:49:00 | Study findings determined the detrimental impact of KIR2DS1, 2DS5, 3DS1, 2DL5 and CxT4 genotype on genetic predisposition to head and neck squamous cell carcinoma in Iranians. | 29408295 |
| 2018-04-14 11:20:00 | KIR2DS1 expression by decidual natural killer cells increases their ability to control placental HCMV infection | 27956621 |
| Type | IDs |
|---|---|
| Synonymous | CD158H, CD158a, p50.1 |
| Gene |
UniProtKB-ID:
KI2S1_HUMAN,
B1N8M6_HUMAN
UniprotKB:
Q14954,
B1N8M6
UniParc:
UPI000165DD18,
UPI0000001313
EMBL:
CU459006,
KP420440,
KP420443,
KU645196,
JX008030,
GU182339,
X89892,
CU633846,
EF423903,
CU041340,
CU464061,
AF022046,
GU182359,
GU182355,
AL133414,
KP420441,
GU182352,
CU466259
Ensembl:
ENSG00000276387,
ENSG00000284120,
ENSG00000275921,
ENSG00000278120,
ENSG00000284150,
ENSG00000276327
KO:
hsa:3806
|
| Nucleutide sequences |
EMBL-CDS:
CAA61982.1,
ANJ04800.1,
AMR59360.1,
AFV74766.1,
AAB95319.1,
AJI81009.1,
ABS18362.1,
AJI81026.1
Ensembl_TRS:
ENST00000617661,
ENST00000644318,
ENST00000611996,
ENST00000643062,
ENST00000639232,
ENST00000639093,
ENST00000616491,
ENST00000615190
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000495438,
ENSP00000482170,
ENSP00000494266,
ENSP00000492347,
ENSP00000483434,
ENSP00000492239,
ENSP00000479102,
ENSP00000480228
RefSeq:
NP_055327.1,
XP_024308310.1,
XP_016885775.1,
XP_011546300.1,
XP_024308313.1,
XP_024308312.1,
XP_024308311.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JNJ6,
UniRef100_Q14954
UniRef90:
UniRef90_Q14953
UniRef50:
UniRef50_P43626
UniGene:
Hs.744319
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员