| Type | Description |
|---|---|
| Definition | acetyl-CoA acetyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis. | 31974474 |
| 2019-02-16 12:03:00 | Silencing ACAT1 attenuates Abeta-induced cytotoxicity and cell apoptosis in SH-SY5Y cells, which may due to the synergistic effect of ACAT1 and COX2 through pathways. | 30541014 |
| 2018-10-20 10:43:00 | High ACAT1 expression is associated with breast cancer. | 30092298 |
| 2018-10-13 11:16:00 | Insulin promotes progression of colon cancer by upregulation of ACAT1. | 29793481 |
| 2017-04-08 10:58:00 | ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase. | 27748876 |
| Type | IDs |
|---|---|
| Synonymous | ACAT, MAT, T2, THIL |
| Gene |
UniProtKB-ID:
THIL_HUMAN,
A0A140VJX1_HUMAN,
A0A5F9ZHJ0_HUMAN
UniprotKB:
P24752,
A0A140VJX1,
A0A5F9ZHJ0
UniParc:
UPI0000136E41,
UPI00001FA2F5,
UPI0003EAF58E
EMBL:
D90228,
BC010942,
HM005511,
D10511,
AK312574,
AP002433,
CH471065
Ensembl:
ENSG00000075239
KO:
hsa:38
|
| Nucleutide sequences |
EMBL-CDS:
BAA01387.1,
BAG35468.1,
EAW67104.1,
AAH10942.1,
BAA14278.1,
EAW67105.1,
AEE61108.1
Ensembl_TRS:
ENST00000265838,
ENST00000299355,
ENST00000672284,
ENST00000673531
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265838,
ENSP00000299355,
ENSP00000500163,
ENSP00000500444
RefSeq:
XP_016873171.1,
NP_001373611.1,
NP_001373610.1,
NP_001373620.1,
NP_000010.1,
XP_024304282.1,
NP_001373614.1,
NP_001373615.1,
NP_001373617.1,
NP_001373606.1,
NP_001373618.1,
NP_001373607.1,
NP_001373608.1,
NP_001373619.1,
NP_001373616.1
|
| Others |
UniRef100:
UniRef100_P24752
UniRef90:
UniRef90_P24752
UniRef50:
UniRef50_P24752
UniGene:
Hs.232375
CCDS:
CCDS8339.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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