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37895 SerT

37895

SerT

Serotonin transporter

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Serotonin transporter

研究结论

Date Results Publications
2018-07-14 11:49:00 show that dSERT mutant animals exhibit an increased survival rate in stress conditions, increased basal motor behavior, and decreased levels in an anxiety-related parameter, centrophobism 28665105
2017-05-13 18:42:00 Data suggest that functional differences between human, and Drosophila melanogaster, and Caenorhabditis elegans serotonin transporters (SERT) in recognition of MDMA (3,4-methylenedioxy-methamphetamine, "ecstasy") as substrate are due to a single amino acid in transmembrane domain 10 (Glu394 in hSERT; Asn484 in dmSERT; Asp517 in ceSERT). 27638414
2010-01-21 00:00:00 These data suggest that a small number of neurons selectively express factor(s) required for 5-HT storage, and potentially for function of dSERT. 16470720

名称对应

Type IDs
Synonymous CG4545, DmSERT, DmSerT, Dmel\CG4545, SERT, Sert, dSERT, dSERT1, dSerT, dSert, dmSERT, dsert, serT
Gene
UniProtKB-ID: SC6A4_DROME, A0A0B4LHJ6_DROME
UniprotKB: P51905, A0A0B4LHJ6
UniParc: UPI0000000FB5
EMBL: U02296, AE013599, U04809, AY071023
EnsemblGenome: FBgn0010414
KO: dme:Dmel_CG4545
Nucleutide sequences
EMBL-CDS: AAA19430.1, AAL48645.1, AAD10615.1, AAF47200.1, AHN56634.1
Gene_ORFName: CG4545, Dmel_CG4545, CG4545
EnsemblGenome_TRS: FBtr0343316, FBtr0072362, FBtr0343316, FBtr0072362
Protein sequencees
EnsemblGenome_PRO: FBpp0309974, FBpp0072269, FBpp0309974, FBpp0072269
RefSeq: NP_523846.2, NP_001286839.1, NP_001369117.1
Others
UniRef100: UniRef100_P51905
UniRef90: UniRef90_P51905
UniRef50: UniRef50_P51905
UniGene: Dm.5365

全选

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研究热度

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