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37867 Dat

37867

Dat

Dopamine N acetyltransferase

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Dopamine N acetyltransferase

研究结论

Date Results Publications
2021-02-27 13:47:00 AANAT1 functions in astrocytes to regulate sleep homeostasis. 32955431
2018-03-26 10:28:00 Data suggest Glu47 acts as general base with apparent pKa of 7.0 in biocatalysis by AANAT; 2 equally active variants exist, with AANATA differing from AANATB by truncation of 35 amino acids from N-terminus. [AANAT; arylalkylamine Nacetyltransferase] 25406072
2017-01-28 10:06:00 Here we report a Drosophila dopamine-related locomotor endophenotype that is shared by pan-neuronal knockdown of orthologs of the ADHD-associated genes Dopamine transporter (DAT1) and Latrophilin (LPHN3), and of a gene causing a monogenic disorder with frequent ADHD comorbidity. 25962619
2016-02-13 11:03:00 Dat is entirely responsible for a pigmentation difference between Drosophila species. 25769982
2012-11-17 11:11:00 Dat possesses a specialized active site structure dedicated to a catalytic mechanism. 22716280

名称对应

Type IDs
Synonymous AA-NAT1, AANAT, AANATA, AANATB, Aanat1, CG3318, DAT, Dat1, Dmel\CG3318, NAT1, aaNAT, aaNAT1, aaNat
Gene
UniProtKB-ID: DNAT_DROME
UniprotKB: Q94521
UniParc: UPI0000077F33, UPI000007C319
EMBL: AE013599, AY118780, Y07964
EnsemblGenome: FBgn0019643
KO: dme:Dmel_CG3318
Nucleutide sequences
EMBL-CDS: AAM50640.1, AAM68307.1, CAA69262.1, AAF47172.1
Gene_ORFName: CG3318
EnsemblGenome_TRS: FBtr0072254, FBtr0072255
Protein sequencees
EnsemblGenome_PRO: FBpp0089101, FBpp0072163
RefSeq: NP_995934.1, NP_523839.2
Others
UniRef100: UniRef100_Q94521
UniRef90: UniRef90_Q94521
UniRef50: UniRef50_Q94521
UniGene: Dm.11356

全选

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