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378435 Mafa

378435

Mafa

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)

protein-coding

Mus musculus

基因描述

Type Description
Definition v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)

研究结论

Date Results Publications
2021-02-20 13:36:00 An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition. 32764399
2020-08-22 15:27:00 Loss of MafA and MafB expression promotes islet inflammation. 31235823
2020-05-30 12:20:00 Here, we observed that treatment with Ad-FIGF was found to enhance MafA and Ngn3-induced reprogramming of BNL CL.2 cells to beta-like cells with the ability of secreting insulin. 31894130
2020-04-18 10:18:00 Kindlin-2, through its C-terminal region, binds to and stabilizes MafA, which activates insulin expression. 31980627
2017-10-07 12:07:00 Data suggest that hepatocytes can be reprogrammed into insulin-producing cells in vivo by transfection of neurogenin-3, Pdx1, and MafA genes using non-viral hydrodynamics injection; this procedure was used in treatment of streptozotocin diabetes; fasting blood glucose was reduced to normal. (Pdx1 = pancreatic and duodenal homeobox 1; MafA = v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A) 28100871

名称对应

Type IDs
Synonymous RIPE3b1
Gene
UniProtKB-ID: MAFA_MOUSE
UniprotKB: Q8CF90
UniParc: UPI00000E901B
EMBL: AB086961
Ensembl: ENSMUSG00000047591
KO: mmu:378435
Nucleutide sequences
EMBL-CDS: BAC20390.1
Ensembl_TRS: ENSMUST00000062002
Protein sequencees
Ensembl_PRO: ENSMUSP00000054226
RefSeq: NP_919331.1
Others
UniRef100: UniRef100_Q8CF90
UniRef90: UniRef90_Q8CF90
UniRef50: UniRef50_Q8CF90
UniGene: Mm.309589
CCDS: CCDS27549.1

全选

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