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3783709 EBNA-1

3783709

EBNA-1

nuclear antigen EBNA-1

protein-coding

Human herpesvirus 4

基因描述

Type Description
Definition nuclear antigen EBNA-1

研究结论

Date Results Publications
2020-09-19 16:26:00 Transcription Activator PAX5 Recruits p300 To Support EBNA1-Driven Transcription. 31941781
2020-06-27 12:29:00 the dissociation of EBNA1 with STUB1, KAP1 and USP7 to increase the SUMO1 modification of both STUB1 and KAP1 for reactivation of lytic replication. Therefore, the EBNA1SIM motif plays an essential role in EBV latency and is a potential therapeutic target against EBV-associated cancers. 32176739
2020-06-20 12:47:00 The Epstein-Barr virus (EBV) nuclear antigen (EBNA)-1 induces the accumulation of reactive oxygen species which enables B-cell immortalization but causes oxidative DNA damage and triggers antiproliferative DNA damage responses. EBV carriage promotes the concomitant activation of oxo-dNTP sanitization and purging pathways, including upregulation of the MTH1, OGG1, and MUTYH. 31511648
2020-03-28 10:11:00 a hypothesis where immune reactivity toward EBNA1 through molecular mimicry with ANO2 contributes to the etiopathogenesis of Multiple sclerosis. 31375628
2020-01-18 10:29:00 Vav1 interacts with EBNA1 via its C-terminal SH3 domain. This interaction suppresses the expression of a pro-apoptotic Bcl-2 family member, Bim, resulting in the resistance of the Burkitt's lymphoma cells to apoptotic inductions. 30833082

名称对应

Type IDs
Gene
UniProtKB-ID: EBNA1_EBVB9, A0A0B6VKU0_EBVG
UniprotKB: P03211, A0A0B6VKU0
UniParc: UPI000000CDDD
EMBL: V01555, M13941, AB850647, AJ507799, AB850654
KO: vg:3783774
Nucleutide sequences
EMBL-CDS: CAD53427.1, AAA45889.1, CAA24816.1, BAQ20317.1, BAQ20136.1
Gene_ORFName: BKRF1
Protein sequencees
Others
UniRef100: UniRef100_P03211
UniRef90: UniRef90_P03211
UniRef50: UniRef50_P03211

全选

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