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3781 KCNN2

3781

KCNN2

potassium calcium-activated channel subfamily N member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium calcium-activated channel subfamily N member 2

研究结论

Date Results Publications
2021-03-06 13:29:00 Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. 33242881
2021-02-06 13:51:00 HDAC2-dependent remodeling of KCa2.2 (KCNN2) and KCa2.3 (KCNN3) K(+) channels in atrial fibrillation with concomitant heart failure. 33310041
2021-01-09 13:32:00 SK2 channel regulation of neuronal excitability, synaptic transmission, and brain rhythmic activity in health and diseases. 32860835
2020-03-28 11:52:00 Immuno-visualization of the subcellular localization of SK2 and SK3 subunits showed a high degree of colocalization, consistent with the formation of heteromeric SK2/SK3 channels. 30922569
2019-07-20 10:04:00 Junctophilin 2, as junctional membrane complex (JMC) protein, is an important regulator of the cardiac SK channels 29055091

名称对应

Type IDs
Synonymous KCa2.2, SK2, SKCA2, SKCa 2, hSK2
Gene
UniProtKB-ID: KCNN2_HUMAN, A0A3F2YNY5_HUMAN
UniprotKB: Q9H2S1, A0A3F2YNY5
UniParc: UPI000013D56A, UPI00001617C4, UPI0005D03516
EMBL: AY258141, AF239613, AF397175, AC025761, CH471086, AK289948, AC093527, KF459898, AC106789, AC113364, BC015371, AC109482, BC117456, AC094088, BC117454
Ensembl: ENSG00000080709
KO: hsa:3781
Nucleutide sequences
EMBL-CDS: BAF82637.1, AAI17455.1, AAP45946.1, AAK84039.1, AAI17457.1, AAG16728.1, EAW48976.1, EAW48975.1, AAH15371.1
Ensembl_TRS: ENST00000610748, ENST00000264773, ENST00000503706, ENST00000512097
Protein sequencees
Ensembl_PRO: ENSP00000421439, ENSP00000264773, ENSP00000483124, ENSP00000427120
RefSeq: NP_740721.1, NP_067627.3, NP_001359162.1, XP_016864946.1, XP_011541691.1, NP_001265133.1
Others
UniRef100: UniRef100_Q9H2S1
UniRef90: UniRef90_Q9H2S1
UniRef50: UniRef50_P70604
UniGene: Hs.98280
CCDS: CCDS43352.1

全选

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