| Type | Description |
|---|---|
| Definition | potassium calcium-activated channel subfamily N member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:25:00 | Data demonstrate that IKCa and SK1 subunits prefer to form heteromeric channels when coexpressed in a heterologous system that will alter their responsiveness to pharmacological tools typically used to define their expression pattern. | 31048549 |
| 2018-09-29 10:27:00 | SK current is increased via the enhanced activation of CaMKII in patients with atrial fibrillation. | 29737974 |
| 2014-09-06 11:02:00 | Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels. | 24434522 |
| 2012-04-07 10:27:00 | Decreased expression of small-conductance Ca2+-activated K+ channels SK1 and SK2 in human chronic atrial fibrillation. | 22154908 |
| 2010-01-21 00:00:00 | IK1-like immunoreactivity is observed in enteric neurons of human colon, with a significant decrease of IK1-positive cells in inflamed colon from patients with Crohn's disease and ulcerative colitis. | 12598727 |
| Type | IDs |
|---|---|
| Synonymous | KCa2.1, SK1, SKCA1, hSK1 |
| Gene |
UniProtKB-ID:
KCNN1_HUMAN
UniprotKB:
Q92952
UniParc:
UPI00000312B7,
UPI00001649F9
EMBL:
AF131944,
AF131948,
AB198191,
AF131942,
AF131945,
U69883,
AF131941,
AF131946,
AF131947,
BC075037,
AF131943,
AF131940
Ensembl:
ENSG00000105642
KO:
hsa:3780
|
| Nucleutide sequences |
EMBL-CDS:
AAH75037.3,
AAB09562.1,
AAD37507.1,
BAD86831.1
Ensembl_TRS:
ENST00000222249
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000476519
RefSeq:
NP_001373905.1,
NP_001373906.1,
NP_001373904.1,
NP_001373903.1,
XP_011526306.1,
NP_002239.2
|
| Others |
UniRef100:
UniRef100_Q92952
UniRef90:
UniRef90_Q92952
UniRef50:
UniRef50_Q92952
UniGene:
Hs.158173
CCDS:
CCDS67611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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