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378 ARF4

378

ARF4

ADP ribosylation factor 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition ADP ribosylation factor 4

研究结论

Date Results Publications
2021-02-27 13:45:00 Class II Arfs require a brefeldin-A-sensitive factor for Golgi association. 32828303
2020-06-20 12:13:00 Study identified two novel sodium iodide symporter (NIS) interactors, valosin-containing protein (VCP) and ADP-ribosylation factor 4 (ARF4), with critical roles in modulating NIS function as well as correlating markedly with clinical outcome in papillary thyroid cancer. ARF4 enhanced NIS vesicular trafficking from the Golgi to the plasma membrane, whereas VCP governed NIS proteolysis. 31672844
2018-07-28 10:06:00 In summary, the authors show here that hepatitis C virus infection is associated with an upregulation of ARF4, which promotes hepatitis C virus replication. Upon hepatitis C virus infection, CREB3 was redistributed to nucleus and activated ARF4 transcription. 28840565
2018-04-14 11:16:00 found ADP-ribosylation factor (ARF) 4 is one of the putative target genes of Mir-221, and the direct binding relationship was further confirmed by dual-luciferase reporter assay. 28057486
2017-09-30 11:13:00 Data suggest that, when compared to intestinal epithelial cells (IECs) from germ-free mice, IECs from mice with commensal bacteria exhibit increased expression of microRNA-21-5p; up-regulation of expression of microRNA-21-5p appears to increase IEC permeability and up-regulates ADP ribosylation factor 4 (Arf4/ARF4) in mouse and human cells. 28760826

名称对应

Type IDs
Synonymous ARF2
Gene
UniProtKB-ID: ARF4_HUMAN
UniprotKB: P18085
UniParc: UPI000013E89E
EMBL: AF104238, AF104233, M36341, AF104236, BC022866, BC003364, AF493883, AK313008, AF104235, BC016325, AF104237, BC008753, AF104234
Ensembl: ENSG00000168374
KO: hsa:378
Nucleutide sequences
EMBL-CDS: AAD54674.1, AAH16325.1, AAH22866.1, AAH03364.1, AAA53081.1, AAM12597.1, AAH08753.1, BAG35844.1
Ensembl_TRS: ENST00000303436
Protein sequencees
Ensembl_PRO: ENSP00000306010
RefSeq: NP_001651.1
Others
UniRef100: UniRef100_P18085
UniRef90: UniRef90_P18085
UniRef50: UniRef50_P18085
UniGene: Hs.652183
CCDS: CCDS2884.1

全选

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