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3779 KCNMB1

3779

KCNMB1

potassium calcium-activated channel subfamily M regulatory beta subunit 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium calcium-activated channel subfamily M regulatory beta subunit 1

研究结论

Date Results Publications
2020-05-16 12:54:00 that epigenetic upregulation of KCNMB1 contributes to increased large-conductance (Big) potassium channel activity in idiopathic pulmonary fibrosis fibroblasts 31486669
2020-02-01 10:19:00 Decreased protein expression and altered intrinsic properties of BKbeta1 channels mediates abnormal vasodilation in the coronary microvasculature of type 2 diabetics. 29850792
2017-12-16 10:31:00 Expression of vascular large-conductance calcium-activated potassium channel Kcnmb1 is regulated by Nrf2 signaling. 28429615
2017-10-07 12:11:00 These results provide further insights into the mechanism of modulation of the different N-terminal regions of the BKCa channel by beta-subunits. 28750098
2017-01-28 10:12:00 By introducing lanthanide binding tags in the extracellular region of the alpha- or beta1-subunit, we determined (i) a basic extracellular map of the BK channel, (ii) beta1-subunit-induced rearrangements of the voltage sensor in alpha-subunits, and (iii) the relative position of the beta1-subunit within the alpha/beta1-subunit complex. 27217576

名称对应

Type IDs
Synonymous BKbeta1, K(VCA)beta, SLO-BETA, hbeta1, hslo-beta, k(VCA)beta-1, slo-beta-1
Gene
UniProtKB-ID: KCMB1_HUMAN
UniprotKB: Q16558
UniParc: UPI000006CF96, UPI0000000DBA
EMBL: U61536, AY044441, CH471062, U42603, U25138, AK313979, BC025707, U38907, U42600, AY515264, U42602, U61537, U42601, AF026002
Ensembl: ENSG00000145936
KO: hsa:3779
Nucleutide sequences
EMBL-CDS: EAW61474.1, AAB61397.1, BAG36693.1, AAB02394.1, AAK95827.1, AAH25707.1, AAB16827.1, AAB16825.1, AAB16826.1, AAB88805.1, AAA81327.1, AAB61396.1, AAS20193.1
Ensembl_TRS: ENST00000521859, ENST00000274629
Protein sequencees
Ensembl_PRO: ENSP00000427940, ENSP00000274629
RefSeq: NP_004128.1
Others
UniRef100: UniRef100_Q16558
UniRef90: UniRef90_Q16558
UniRef50: UniRef50_Q16558
UniGene: Hs.484099, Hs.744947
CCDS: CCDS4373.1

全选

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