| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 17 like family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 15:57:00 | DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer. | 30778200 |
| 2019-11-30 11:43:00 | DUB3 functions as a novel cyclin A regulator through maintaining cyclin A stability. | 30935108 |
| 2019-05-25 10:57:00 | further analysis revealed 2 hemizygous deletions in the grandmother that segregate in several of her affected offspring. The first deletion was found in the UGT2B28 locus, spanning 7 informative sequence variants across at least 14 kb. The second deletion, located in USP17L2, spans 3 informative variants across at least 2 kb. On the whole, the findings of the presents study implicate 2 additional genes in the pathogenesis | 30628680 |
| 2019-05-04 11:41:00 | our results revealed the essential role of the MGMT-DUB3-MCL1 axis in the chemoresistance of ovarian cancer and identified that a combined treatment with HDACis and PaTrin-2 is an effective method for overcoming chemoresistance in ovarian cancer. | 30718431 |
| 2019-03-23 11:05:00 | DUB3 promotes BET inhibitor resistance and cancer progression by deubiquitinating BRD4. | 30057199 |
| Type | IDs |
|---|---|
| Synonymous | DUB-3, DUB3, USP17 |
| Gene |
UniProtKB-ID:
U17L2_HUMAN
UniprotKB:
Q6R6M4
UniParc:
UPI0000198137
EMBL:
AY509884,
AC130366
Ensembl:
ENSG00000223443
KO:
hsa:377630
|
| Nucleutide sequences |
EMBL-CDS:
AAR91701.1
Ensembl_TRS:
ENST00000333796
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333329
RefSeq:
NP_958804.2
|
| Others |
UniRef100:
UniRef100_Q6R6M4
UniRef90:
UniRef90_Q6R6M4
UniRef50:
UniRef50_Q6R6M4
UniGene:
Hs.531448
CCDS:
CCDS43713.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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