| Type | Description |
|---|---|
| Definition | potassium two pore domain channel subfamily K member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:31:00 | A regulatory domain in the K2P2.1 (TREK-1) carboxyl-terminal allows for channel activation by monoterpenes. | 32320829 |
| 2021-02-02 13:25:00 | Astrocytic AEG-1 regulates expression of TREK-1 under acute hypoxia. | 31782179 |
| 2020-05-23 11:59:00 | The activity of TREK-1 has a key role for the correct functioning of the alveolar epithelium. | 30805940 |
| 2020-02-01 10:53:00 | The frequencies of rs758937019-CT genotype (P = 0.0016) and rs758937019-T allele (P = 0.0022) were significantly higher in the group with overactive lower urinary tract symptoms | 30350878 |
| 2020-01-11 11:03:00 | The PIP2-dependent converse regulation of TREKs by Lys and R3-pCt with Gly implies structural flexibility. | 30576235 |
| Type | IDs |
|---|---|
| Synonymous | K2p2.1, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e |
| Gene |
UniProtKB-ID:
KCNK2_HUMAN,
U3N834_HUMAN,
U3N6F0_HUMAN,
Q6ZW95_HUMAN
UniprotKB:
O95069,
U3N834,
U3N6F0,
Q6ZW95
UniParc:
UPI0000031580,
UPI000050AB10,
UPI00004E1DDD,
UPI00001C08EA,
UPI000013D4B8
EMBL:
BC143586,
AF129399,
BC101693,
AC092804,
AY552980,
KF182338,
AK315249,
AF004711,
AF171068,
AC099675,
KF182339,
AK123409,
AY552981,
CH471100,
BC069462,
EF165334,
AK291483,
EF165335,
AL583830,
BC101695
Ensembl:
ENSG00000082482
KO:
hsa:3776
|
| Nucleutide sequences |
EMBL-CDS:
AAH69462.1,
AAT49015.2,
EAW93349.1,
AAD01203.1,
AAF89743.1,
BAF84172.1,
AAI01696.1,
BAG37671.1,
EAW93347.1,
AAT49016.1,
ABM47413.1,
AAI43587.1,
AAD47569.1,
ABM47414.1,
AAI01694.1,
AGW27105.1,
AGW27106.1,
BAC85609.1
Ensembl_TRS:
ENST00000391894,
ENST00000444842,
ENST00000391895,
ENST00000467031,
ENST00000486921
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000375764,
ENSP00000420203,
ENSP00000375765,
ENSP00000394033,
ENSP00000418706
RefSeq:
XP_011507825.1,
XP_011507826.1,
NP_055032.1,
NP_001017424.1,
XP_011507824.1,
XP_016856737.1,
NP_001017425.2,
XP_016856738.1
|
| Others |
UniRef100:
UniRef100_O95069,
UniRef100_U3N6F0,
UniRef100_U3N834,
UniRef100_Q6ZW95
UniRef90:
UniRef90_Q920B6,
UniRef90_Q6ZW95
UniRef50:
UniRef50_Q6ZW95,
UniRef50_Q920B6
UniGene:
Hs.497745
CCDS:
CCDS41466.1,
CCDS31024.1,
CCDS41467.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员