| Type | Description |
|---|---|
| Definition | potassium two pore domain channel subfamily K member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:29:00 | Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K(+) channel. | 31806709 |
| 2017-06-24 10:10:00 | Dynamics of the TWIK-1 Channel | 27558721 |
| 2017-06-03 12:25:00 | Our data indicate that TWIK-1 has a highly conserved role in cardiac function and is required for normal heart rate and atrial morphology. Despite the functional importance of TWIK-1 in the atrium, genetic variation in KCNK1 is not a common primary cause of human AF. | 27103460 |
| 2015-11-21 10:39:00 | TWIK-1 protein possesses a hydrophobic barrier deep within the inner pore | 25001086 |
| 2012-02-25 10:39:00 | Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells | 21964404 |
| Type | IDs |
|---|---|
| Synonymous | DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1 |
| Gene |
UniProtKB-ID:
KCNK1_HUMAN,
A0A024R3T2_HUMAN
UniprotKB:
O00180,
A0A024R3T2
UniParc:
UPI0000127A50
EMBL:
CH471098,
AL356357,
U90065,
BC018051,
U76996,
U33632
Ensembl:
ENSG00000135750
KO:
hsa:3775
|
| Nucleutide sequences |
EMBL-CDS:
AAB51147.1,
EAW69989.1,
AAH18051.1,
AAB01688.1,
AAB97878.1,
EAW69990.1
Gene_ORFName:
hCG_15518
Ensembl_TRS:
ENST00000366621
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355580
RefSeq:
NP_002236.1,
XP_011542486.1
|
| Others |
UniRef100:
UniRef100_O00180
UniRef90:
UniRef90_O00180
UniRef50:
UniRef50_O00180
UniGene:
Hs.208544
CCDS:
CCDS1599.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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