| Type | Description |
|---|---|
| Definition | Phosphotidylinositol 3 kinase 59F |
| Date | Results | Publications |
|---|---|---|
| 2017-02-25 11:22:00 | lowered expression of Atg6 or Pi3K59F in Ddc-Gal4-expressing neurons results in decreased longevity and associated age-dependent loss of locomotor ability. Inhibition of Atg6 or Pi3K59F together with overexpression of the sole pro-survival Bcl-2 Drosophila homolog Buffy in Ddc-Gal4-expressing neurons resulted in further decrease in the survival | 27813607 |
| 2015-03-07 11:33:00 | The UVRAG-containing PI3K (III) complex is required for receptor downregulation through endolysosomal degradation and for the establishment of proper cell polarity in the developing wing. | 25006588 |
| 2010-04-19 11:29:00 | crystal structure of Vps34 at 2.9 A resolution, which revealed a constricted adenine-binding pocket; the phosphoinositide-binding loop & the carboxyl-terminal helix of Vps34 mediate catalysis on membranes & suppress futile adenosine triphosphatase cycles | 20339072 |
| 2010-01-21 00:00:00 | Vps34 is regulated by TOR-dependent nutrient signals directly at sites of autophagosome formation. | 18474623 |
| Type | IDs |
|---|---|
| Synonymous | CG5373, DmVps34, Dmel\CG5373, PI(3)K, PI3K, PI3K-59F, PI3K_59F, PI[[3]]K, Pi3K_59F, Pi3k59F, VPS34, Vps34, dPI3K, dVps34, dVps34/PI3K59F, vps34 |
| Gene |
UniProtKB-ID:
Q9W1M7_DROME
UniprotKB:
Q9W1M7
UniParc:
UPI0000078F2E
EMBL:
AY058362,
AE013599
EnsemblGenome:
FBgn0015277
KO:
dme:Dmel_CG5373
|
| Nucleutide sequences |
EMBL-CDS:
AAF47030.2,
AAL13591.1
Gene_ORFName:
CG5373,
Dmel_CG5373
EnsemblGenome_TRS:
FBtr0072064
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0071973
RefSeq:
NP_477133.1
|
| Others |
UniRef100:
UniRef100_Q9W1M7
UniRef90:
UniRef90_Q9W1M7
UniRef50:
UniRef50_Q8NEB9
UniGene:
Dm.1676
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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