| Type | Description |
|---|---|
| Definition | RNA on the X 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 11:41:00 | our research provides structural insights into the interactions between MLE dsRBDs and R2H1 and facilitates a deeper understanding of the mechanism by which MLE tandem dsRBDs play an indispensable role in specific recognition of roX and the assembly of the MSL-DCC in Drosophila dosage compensation. | 30649456 |
| 2019-07-27 10:26:00 | the initial targeting of the dosage compensation lncRNA, roX1, to chromatin entry sites on the X chromosome is cell-type-specific, differing in neural stem cells and salivary glands | 29323275 |
| 2019-03-09 11:36:00 | We have created a new mutant allele of roX2 and show that roX1 and roX2 have partly separable functions in dosage compensation. Loss of roX1 results in reduced expression of the genes on the X-chromosome, while loss of roX2 leads to male-specific lethal-independent upregulation of genes with male-biased testis-specific transcription. | 30532158 |
| 2018-03-10 11:02:00 | in clamp null females roX gene expression is activated, whereas in clamp null males roX gene expression is reduced. Therefore, CLAMP regulates roX abundance in a sex-specific manner. | 27995349 |
| 2012-09-08 11:18:00 | the expression of roX1 gene is instead controlled through an autoregulatory loop; the production of roX1 and msl2, two key components of the MSL complex, are coordinated to meet the dosage compensation demands of the male cell. | 22438819 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:GH10432, CR32777, Dmel\CR32777, EG:EG0002.2, RoX1, chrX:3706836..3706970, roX, rox-1, rox1 |