| Type | Description |
|---|---|
| Definition | inactivation no afterpotential D |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 12:33:00 | Guided by the structure of the INAD-NORPA complex, we discover that INADL is probably a mammalian counterpart of INAD. The INADL PDZ89 tandem specifically binds to PLCb4 with a mode that is strikingly similar to that of the INAD-NORPA complex, as revealed by the structure of the INADL PDZ89-PLCb4 CC-PBM complex. | 30526850 |
| 2016-12-17 10:24:00 | show that INAD PDZ3 binds to the TRP channel tail with a new mechanism. A 15-residue C-terminal tail of TRP forms a b hairpin structure and binds to a surface of INAD PDZ3 outside the canonical target-binding aB/bB groove. Amino acid residues from both strands of the TRP b hairpin are engaged in binding, and thus the INAD PDZ3/TRP interaction is highly specific and with high affinity. | 26853938 |
| 2011-09-03 10:40:00 | Through biochemical and structural studies, study shows that the redox potential of PDZ5 is allosterically regulated by its interaction with another INAD domain, PDZ4. | 21703451 |
| 2010-10-04 11:28:00 | genetic screen of the third chromosome for mutations that result in mislocalization of an INAD-GFP fusion protein | 20404479 |
| 2010-01-21 00:00:00 | TRP associates with INAD via its last 14 residues to facilitate its regulation by that fine-tunes the visual signaling | 18036153 |
| Type | IDs |
|---|---|
| Synonymous | CG3504, Dmel\CG3504, INAD, Ina-D, InaD |
| Gene |
UniProtKB-ID:
INAD_DROME,
D3DMF9_DROME
UniprotKB:
Q24008,
D3DMF9
UniParc:
UPI000000C35C,
UPI0001C47B4F
EMBL:
BT120028,
AF245280,
U15803,
AE013599,
BT004473
EnsemblGenome:
FBgn0001263
KO:
dme:Dmel_CG3504
|
| Nucleutide sequences |
EMBL-CDS:
AAF81203.1,
AAO42637.1,
AAC36490.1,
AAF46915.1,
ADA53567.1,
AFH08223.1
Gene_ORFName:
CG3504,
Dmel_CG3504,
CG3504
EnsemblGenome_TRS:
FBtr0071909,
FBtr0305132
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0071820,
FBpp0293662
RefSeq:
NP_001246470.1,
NP_726260.1
|
| Others |
UniRef100:
UniRef100_D3DMF9,
UniRef100_Q24008
UniRef90:
UniRef90_Q24008
UniRef50:
UniRef50_Q24008
UniGene:
Dm.2964
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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