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3757 KCNH2

3757

KCNH2

potassium voltage-gated channel subfamily H member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium voltage-gated channel subfamily H member 2

研究结论

Date Results Publications
2021-04-13 10:13:00 Regulation of Kv11.1 Isoform Expression by Polyadenylate Binding Protein Nuclear 1. 33467093
2021-03-20 13:35:00 Lipid regulation of hERG1 channel function. 33658490
2021-02-06 13:49:00 Variant frequencies of KCNQ1, KCNH2, and SCN5A in a Chinese inherited arrhythmia cohort and other disease cohorts undergoing genetic testing. 31696929
2021-02-02 13:23:00 The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine. 32147975
2020-12-19 13:44:00 Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia. 33147278

名称对应

Type IDs
Synonymous ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
Gene
UniProtKB-ID: KCNH2_HUMAN, A0A090N7W1_HUMAN, Q15BH2_HUMAN, A0A090N8Q0_HUMAN, A0A090N7X5_HUMAN
UniprotKB: Q12809, A0A090N7W1, Q15BH2, A0A090N8Q0, A0A090N7X5
UniParc: UPI000002ACA2, UPI000002ACA3, UPI0000225C8B, UPI0001A6169F, UPI0000D8A46A, UPI0001D322F3, UPI0000062255
EMBL: AJ010543, AC006343, AJ512214, AJ010546, AJ010551, AF052728, AJ010549, AJ010541, AF363636, AJ010550, AB009071, AJ010544, AJ010547, BC004311, DQ525913, U04270, AJ010539, AJ010548, AJ010545, FJ938021, CH471173, BC001914, AJ010538, AJ010540, AB044806, AJ010542, AC011234, AACC02000108, AJ609614, DQ784808
Ensembl: ENSG00000055118
KO: hsa:3757
Nucleutide sequences
EMBL-CDS: BAB19682.1, BAA37096.1, EAW54072.1, AAH01914.2, ACR24650.1, AAC69709.1, CAE82156.1, CAA09232.1, AAH04311.2, AAA62473.1, EAW54075.1, CAD54447.1, AAL37559.1, ABQ01243.1, EAW54073.1, EAL24493.1, ABF71886.1, EAL24491.1, EAL24492.1
Gene_ORFName: tcag7.786, hCG_18699, tcag7.786, tcag7.786
Ensembl_TRS: ENST00000262186, ENST00000330883
Protein sequencees
Ensembl_PRO: ENSP00000328531, ENSP00000262186
RefSeq: NP_742053.1, XP_011514488.1, XP_011514487.1, XP_016867685.1, NP_742054.1, NP_001191727.1, XP_016867684.1, NP_000229.1
Others
UniRef100: UniRef100_Q12809, UniRef100_A0A090N7W1, UniRef100_Q15BH2, UniRef100_A0A090N7X5
UniRef90: UniRef90_Q12809, UniRef90_A0A090N7W1, UniRef90_A0A2K5XDB8
UniRef50: UniRef50_A0A2K5XDB8, UniRef50_O35219-3, UniRef50_Q12809
UniGene: Hs.647099
CCDS: CCDS5910.1, CCDS5911.1

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