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3751 KCND2

3751

KCND2

potassium voltage-gated channel subfamily D member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium voltage-gated channel subfamily D member 2

研究结论

Date Results Publications
2021-02-13 13:23:00 Potassium voltage-gated channel subfamily D member 2 induces an aggressive phenotype in lung adenocarcinoma. 32977724
2021-01-23 13:01:00 Modulation of Kv4.2/KChIP3 interaction by the ceroid lipofuscinosis neuronal 3 protein CLN3. 32641494
2019-09-21 11:50:00 The atrial-specific phenotype suggests that targeting Kv4.2 might be effective in the treatment of nocturnal paroxysmal atrial fibrillation, avoiding adverse ventricular effects. 30571183
2019-05-25 12:18:00 KCND2 upregulation is a valuable prognostic biomarker in gastric cancer patients, in terms of overall survival and recurrence-free survival. 30051729
2018-08-25 11:52:00 A mutation, V404M, in the Kv4.2 channel subunit is associated with infant-onset epilepsy and autism. V404M enhances inactivation of channels that have not opened but dramatically impairs inactivation after opening. Authors show that increased side-chain volume is largely responsible for these seemingly paradoxical effects. 29581270

名称对应

Type IDs
Synonymous KV4.2, RK5
Gene
UniProtKB-ID: KCND2_HUMAN, A4D0V9_HUMAN
UniprotKB: Q9NZV8, A4D0V9
UniParc: UPI0000073D37
EMBL: CH236947, AB028967, AC004888, CH471070, AJ010969, AF142568, AF166008, BC110449, AF166007, BC110450, AC004946, AF121104
Ensembl: ENSG00000184408
KO: hsa:3751
Nucleutide sequences
EMBL-CDS: AAI10451.1, AAC83405.1, AAD52159.1, BAA82996.2, CAB56841.1, AAF65618.1, AAI10450.1, AAD22053.1, EAL24350.1, EAW83541.1
Gene_ORFName: tcag7.101, hCG_2039708
Ensembl_TRS: ENST00000331113
Protein sequencees
Ensembl_PRO: ENSP00000333496
RefSeq: XP_011514467.1, NP_036413.1
Others
UniRef100: UniRef100_Q9NZV8
UniRef90: UniRef90_Q63881
UniRef50: UniRef50_Q63881
UniGene: Hs.654739
CCDS: CCDS5776.1

全选

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