| Type | Description |
|---|---|
| Definition | platelet endothelial aggregation receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis. | 32541641 |
| 2020-08-01 14:32:00 | PEAR1 acts as a negative regulator in the proliferation of pulmonary microvascular endothelial cells in acute lung injury model via the PI3K/AKT pathway. | 31678362 |
| 2020-08-01 10:28:00 | Study reports that PEAR1 methylation is a marker of platelet activation and whole blood cells count variability, in turn regulating the underlying inflammatory status of an individual. | 31665082 |
| 2020-05-16 12:04:00 | About 15% of Chinese patients undergoing coronary stent implantation for acute coronary syndrome or stable coronary artery disease were AA homozygotes for PEAR1 rs12041331. These patients had approximately 3-fold increase in MACE risk at 30 days. | 31018667 |
| 2020-03-21 12:25:00 | Results establish PEAR1 as the major signaling receptor for natural fucose-based polysaccharides and synthetic glycopolymers in human, but not in mouse, platelets. | 30700416 |
| Type | IDs |
|---|---|
| Synonymous | JEDI, MEGF12 |
| Gene |
UniProtKB-ID:
PEAR1_HUMAN
UniprotKB:
Q5VY43
UniParc:
UPI000045889A
EMBL:
AL356104,
AL158169,
AK074121
Ensembl:
ENSG00000187800
KO:
hsa:375033
|
| Nucleutide sequences |
EMBL-CDS:
BAB84947.1
Ensembl_TRS:
ENST00000292357,
ENST00000338302
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000292357,
ENSP00000344465
RefSeq:
XP_011507812.1,
XP_016856729.1,
NP_001340612.1,
XP_016856728.1,
XP_016856723.1,
XP_011507813.1,
XP_016856731.1,
NP_001340611.1,
XP_011507814.1,
NP_001073940.1,
XP_016856730.1,
XP_016856724.1,
XP_016856725.1,
XP_016856727.1,
XP_005245198.1
|
| Others |
UniRef100:
UniRef100_Q5VY43
UniRef90:
UniRef90_Q5VY43
UniRef50:
UniRef50_Q5VY43
UniGene:
Hs.142003
CCDS:
CCDS30892.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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