| Type | Description |
|---|---|
| Definition | suprabasin |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:12:00 | SBSN expression was observed in human clinical specimens of colon and ovarian carcinomas, as well as in circulating tumour cells and metastases of the 4T1 mouse model. The association of SBSN expression with progressive stages of cancer development indicates its role in cancer evolution and therapy resistance. | 30919591 |
| 2019-12-14 11:29:00 | Epidermal SBSN expression was decreased in atopic dermatitis (AD) lesional skin compared to healthy skin. The SBSN serum levels were significantly lower in AD patients than in normal subjects. Study results suggested that SBSN regulates normal epidermal barrierand has an anti-apoptotic activity, and its deficiency is involved in the pathogenesis of AD. | 31399284 |
| 2017-05-27 10:36:00 | SCARA5 and SBSN shown to have modest effects on cell proliferation or collagen gel contraction and maybe associated with peripheral vein graft patency. | 25935274 |
| 2016-12-31 10:10:00 | we demonstrated that upregulation of suprabasin activated the Wnt/b-catenin signaling pathway and led to nuclear localization of b-catenin and upregulation of Cyclin D1 and c-Myc. Together, our results suggest that suprabasin plays an important oncogenic role in promoting proliferation and tumorigenesis of esophageal squamous cell carcinoma . | 26899563 |
| 2015-02-21 10:09:00 | Findings suggest that SBSN is involved in the angiogenic potential of tumor endothelial cells (TEC) and may be a novel TEC marker. | 25283635 |
| Type | IDs |
|---|---|
| Synonymous | UNQ698 |
| Gene |
UniProtKB-ID:
SBSN_HUMAN
UniprotKB:
Q6UWP8
UniParc:
UPI000059D6E7,
UPI0000035981
EMBL:
BX648076,
AY358701,
BC063640,
AK291305,
AC002389
Ensembl:
ENSG00000189001
KO:
hsa:374897
|
| Nucleutide sequences |
EMBL-CDS:
AAQ89064.1,
BAF83994.1,
AAH63640.1
Gene_ORFName:
UNQ698/PRO1343
Ensembl_TRS:
ENST00000518157,
ENST00000452271
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000428771,
ENSP00000430242
RefSeq:
NP_001159507.1,
XP_011525233.1,
NP_940940.1,
NP_001159506.1,
XP_011525232.1,
XP_011525231.1
|
| Others |
UniRef100:
UniRef100_Q6UWP8
UniRef90:
UniRef90_Q6UWP8
UniRef50:
UniRef50_Q6UWP8
UniGene:
Hs.433484
CCDS:
CCDS54253.1,
CCDS12464.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员