| Type | Description |
|---|---|
| Definition | checkpoint kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 13:31:00 | these results suggest that MDV disables the ATR-Chk1 pathway through activation to benefit its replication. | 30787154 |
| 2016-09-03 11:38:00 | Pericentriolar material expansion depended on CHK1 kinase. Nuclear CHK1 activation after DNA damage mirrored PCM expansion, suggesting a PCM/damage feedback loop whereby CHK1 regulates pericentrin-dependent PCM expansion to control its own activation. | 26165835 |
| 2016-02-06 11:31:00 | BRCA1 promotes G2 arrest and cell death by prolonging phosphorylation of Chk1 on serine 345 after DNA damage to sustain arrest. | 26324327 |
| 2010-02-08 11:22:00 | Chk1 signalling causes centrosome amplification after ionizing radiation by upregulating Cdk2 activity through activating phosphorylation. | 19838212 |
| 2010-01-21 00:00:00 | These results suggest a mechanism through which Chk1 could protect against tumorigenesis through its role in spindle checkpoint signaling. | 17276342 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CHK1_CHICK
UniprotKB:
Q8AYC9
UniParc:
UPI00000FE189
EMBL:
AF525027
KO:
gga:374260
|
| Nucleutide sequences |
EMBL-CDS:
AAN33019.1
|
| Protein sequencees |
RefSeq:
XP_015153425.1,
XP_015153427.1,
NP_989676.1
|
| Others |
UniRef100:
UniRef100_Q8AYC9
UniRef90:
UniRef90_Q8AYC9
UniRef50:
UniRef50_O14757
UniGene:
Gga.4288,
Gga.48286
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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