| Type | Description |
|---|---|
| Definition | matrix metallopeptidase 14a (membrane-inserted) |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 10:55:00 | Based on our observations as well as previously published data, we hypothesize that MMP14's catalytic activity is the prime determinant of disease severity. Given the limitations of our in vitro assays in addressing the consequences of MMP14 dysfunction, we generated a novel mmp14a/b knockout zebrafish model | 29741626 |
| 2013-07-06 11:24:00 | Data indicate Mmp14a-dependent retinal defects lead to microphthalmia; Mmp14b, on the contrary, does not appear to alter retinal neurogenesis. | 23326364 |
| 2012-10-27 11:21:00 | VANGL2 regulates the endocytosis and cell-surface availability of MMP14 in a manner that is dependent on focal adhesion kinase. | 22357946 |
| 2011-02-26 10:58:00 | Data suggest that the MT1-MMP-PTK7 axis plays an important role in normal embryogenesis. | 20837484 |
| 2010-01-21 00:00:00 | MT-MMPalpha and beta were expressed through at least the first 72 h of development and this expression was targeted to the cell surface | 12853038 |
| Type | IDs |
|---|---|
| Synonymous | cb386, sb:cb386, wu:fb72b09 |
| Gene |
UniProtKB-ID:
Q7T2J2_DANRE
UniprotKB:
Q7T2J2
UniParc:
UPI00001AAD9F
EMBL:
AY324196,
BC131864
KO:
dre:373882
|
| Nucleutide sequences |
EMBL-CDS:
AAP74483.1,
AAI31865.1
|
| Protein sequencees |
RefSeq:
NP_919397.1
|
| Others |
UniRef100:
UniRef100_Q7T2J2
UniRef90:
UniRef90_F1Q899
UniRef50:
UniRef50_F1Q899
UniGene:
Dr.29852
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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