| Type | Description |
|---|---|
| Definition | receptor-interacting serine-threonine kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 10:36:00 | these results firstly demonstrate the antibacterial property of the complete histone H2A against gram-negative bacteria E. piscicida in vivo and the correlation between zebrafish histone H2A and RIP2 adaptor protein on the transcriptional regulation of antibacterial genes and MHC related genes. | 31336107 |
| 2019-06-15 10:27:00 | Collectively, our works highlight the similarity and discrepancy of NOD1 and RIP2 in the regulation of immune signaling pathways in the zebrafish early ontogenesis, and confirm the crucial role of RIP2 in NLRs signaling and MHC antigen presentation, but not for MAPK and PI3K/Akt pathways | 29692779 |
| 2019-02-23 12:46:00 | unctional analyses of RIPK2 activity in zebrafish embryos indicated that the variant RIPK2104Asp protein is hyperactive in its signaling capacity, with augmented ability to activate the innate immune response and the NF-kappaB pathway and to promote upregulation of OA-associated genes | 29659823 |
| 2017-02-25 11:18:00 | The expression of NOD2 and RIPK2 in ZF4 cells was constitutive and induced by infection with Edwardsiella tarda and spring viremia of carp virus (SVCV). NOD2 and RIPK2 can activate NF-kappaB and IFN promoters, inducing significantly antiviral defense against SVCV infection. RIPK2 also has a role in inhibiting the bacterial replication. | 27235368 |
| Type | IDs |
|---|---|
| Synonymous | RICK |
| Gene |
UniProtKB-ID:
Q4V958_DANRE
UniprotKB:
Q4V958
UniParc:
UPI0000520B03
EMBL:
BC097049
KO:
dre:373874
|
| Nucleutide sequences |
EMBL-CDS:
AAH97049.1
|
| Protein sequencees |
RefSeq:
NP_919392.2
|
| Others |
UniRef100:
UniRef100_Q4V958
UniRef90:
UniRef90_Q4V958
UniRef50:
UniRef50_Q4V958
UniGene:
Dr.150902
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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