| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 50 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-15 11:36:00 | verexpression of USP50 has no effect on Ku70 mRNA levels, while it reduces Ku70 protein levels by promoting Ku70 degradation, suggesting that USP50 may indirectly regulate Ku70 protein stability. | 29101126 |
| 2017-05-27 10:57:00 | the deubiquitinating enzyme USP50 binds to the ASC protein and subsequently regulates the inflammasome signaling pathway. | 28094437 |
| 2011-02-26 11:19:00 | USP50 may act through a HSP90-dependent mechanism to counteract CDC25B mitotic inducing activity and prevent Wee1 degradation. | 20930503 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP50_HUMAN
UniprotKB:
Q70EL3
UniParc:
UPI0001CB7F8F,
UPI0000232F03
EMBL:
BN000339,
AC012170,
AJ583818
Ensembl:
ENSG00000170236
KO:
hsa:373509
|
| Nucleutide sequences |
EMBL-CDS:
CAE48395.1,
CAE47745.2
Ensembl_TRS:
ENST00000532404
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434676
RefSeq:
NP_987090.2
|
| Others |
UniRef100:
UniRef100_Q70EL3
UniRef90:
UniRef90_Q70EL3
UniRef50:
UniRef50_Q70EL3
UniGene:
Hs.677758
CCDS:
CCDS53944.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29101126 |
J. Investig. Med. Junting Cai , Jianxin Wei , Valerie Schrott , Jing Zhao , Grant Bullock , Yutong Zhao |
2018-01-01 | - |
| 28700943 |
A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells. Cell Rep Timothy D Martin , Danielle R Cook , Mei Yuk Choi , Mamie Z Li , Kevin M Haigis , Stephen J Elledge |
2017-07-11 | - |
| 28094437 |
FEBS Lett. Jae Young Lee , Dongyeob Seo , Jiyeon You , Sehee Chung , Jin Seok Park , Ji-Hyung Lee , Su Myung Jung , Youn Sook Lee , Seok Hee Park |
2017-02-01 | - |
| 27801882 |
USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA. Cell Res Man Zhang , Meng-Xin Zhang , Qiang Zhang , Gao-Feng Zhu , Lei Yuan , Dong-Er Zhang , Qiyun Zhu , Jing Yao , Hong-Bing Shu , Bo Zhong |
2016-12-01 | - |
| 24952745 |
Nat. Genet. Dan E Arking , Sara L Pulit , Lia Crotti , Pim van der Harst , Patricia B Munroe , Tamara T Koopmann , Nona Sotoodehnia , Elizabeth J Rossin , Michael Morley , Xinchen Wang , Andrew D Johnson , Alicia Lundby , DanÃel F Gudbjartsson , Peter A Noseworthy , Mark Eijgelsheim , Yuki Bradford , Kirill V Tarasov , Marcus Dörr , Martina Müller-Nurasyid , Annukka M Lahtinen , Ilja M Nolte , Albert Vernon Smith , Joshua C Bis , Aaron Isaacs , Stephen J Newhouse , Daniel S Evans , Wendy S Post , Daryl Waggott , Leo-Pekka Lyytikäinen , Andrew A Hicks , Lewin Eisele , David Ellinghaus , Caroline Hayward , Pau Navarro , Sheila Ulivi , Toshiko Tanaka , David J Tester , Stéphanie Chatel , Stefan Gustafsson , Meena Kumari , Richard W Morris , à sa T Naluai , Sandosh Padmanabhan , Alexander Kluttig , Bernhard Strohmer , Andrie G Panayiotou , Maria Torres , Michael Knoflach , Jaroslav A Hubacek , Kamil Slowikowski , Soumya Raychaudhuri , Runjun D Kumar , Tamara B Harris , Lenore J Launer , Alan R Shuldiner , Alvaro Alonso , Joel S Bader , Georg Ehret , Hailiang Huang , W H Linda Kao , James B Strait , Peter W Macfarlane , Morris Brown , Mark J Caulfield , Nilesh J Samani , Florian Kronenberg , Johann Willeit , CARe Consortium , COGENT Consortium , J Gustav Smith , Karin H Greiser , Henriette Meyer Zu Schwabedissen , Karl Werdan , Massimo Carella , Leopoldo Zelante , Susan R Heckbert , Bruce M Psaty , Jerome I Rotter , Ivana Kolcic , Ozren PolaÅ¡ek , Alan F Wright , Maura Griffin , Mark J Daly , DCCT/EDIC , David O Arnar , Hilma Hólm , Unnur Thorsteinsdottir , eMERGE Consortium , Joshua C Denny , Dan M Roden , Rebecca L Zuvich , Valur Emilsson , Andrew S Plump , Martin G Larson , Christopher J O'Donnell , Xiaoyan Yin , Marco Bobbo , Adamo P D'Adamo , Annamaria Iorio , Gianfranco Sinagra , Angel Carracedo , Steven R Cummings , Michael A Nalls , Antti Jula , Kimmo K Kontula , Annukka Marjamaa , Lasse Oikarinen , Markus Perola , Kimmo Porthan , Raimund Erbel , Per Hoffmann , Karl-Heinz Jöckel , Hagen Kälsch , Markus M Nöthen , HRGEN Consortium , Marcel den Hoed , Ruth J F Loos , Dag S Thelle , Christian Gieger , Thomas Meitinger , Siegfried Perz , Annette Peters , Hanna Prucha , Moritz F Sinner , Melanie Waldenberger , Rudolf A de Boer , Lude Franke , Pieter A van der Vleuten , Britt Maria Beckmann , Eimo Martens , Abdennasser Bardai , Nynke Hofman , Arthur A M Wilde , Elijah R Behr , Chrysoula Dalageorgou , John R Giudicessi , Argelia Medeiros-Domingo , Julien Barc , Florence Kyndt , Vincent Probst , Alice Ghidoni , Roberto Insolia , Robert M Hamilton , Stephen W Scherer , Jeffrey Brandimarto , Kenneth Margulies , Christine E Moravec , Fabiola del Greco M , Christian Fuchsberger , Jeffrey R O'Connell , Wai K Lee , Graham C M Watt , Harry Campbell , Sarah H Wild , Nour E El Mokhtari , Norbert Frey , Folkert W Asselbergs , Irene Mateo Leach , Gerjan Navis , Maarten P van den Berg , Dirk J van Veldhuisen , Manolis Kellis , Bouwe P Krijthe , Oscar H Franco , Albert Hofman , Jan A Kors , André G Uitterlinden , Jacqueline C M Witteman , Lyudmyla Kedenko , Claudia Lamina , Ben A Oostra , Gonçalo R Abecasis , Edward G Lakatta , Antonella Mulas , Marco Orrú , David Schlessinger , Manuela Uda , Marcello R P Markus , Uwe Völker , Harold Snieder , Timothy D Spector , Johan Ãrnlöv , Lars Lind , Johan Sundström , Ann-Christine Syvänen , Mika Kivimaki , Mika Kähönen , Nina Mononen , Olli T Raitakari , Jorma S Viikari , Vera Adamkova , Stefan Kiechl , Maria Brion , Andrew N Nicolaides , Bernhard Paulweber , Johannes Haerting , Anna F Dominiczak , Fredrik Nyberg , Peter H Whincup , Aroon D Hingorani , Jean-Jacques Schott , Connie R Bezzina , Erik Ingelsson , Luigi Ferrucci , Paolo Gasparini , James F Wilson , Igor Rudan , Andre Franke , Thomas W Mühleisen , Peter P Pramstaller , Terho J Lehtimäki , Andrew D Paterson , Afshin Parsa , Yongmei Liu , Cornelia M van Duijn , David S Siscovick , Vilmundur Gudnason , Yalda Jamshidi , Veikko Salomaa , Stephan B Felix , Serena Sanna , Marylyn D Ritchie , Bruno H Stricker , Kari Stefansson , Laurie A Boyer , Thomas P Cappola , Jesper V Olsen , Kasper Lage , Peter J Schwartz , Stefan Kääb , Aravinda Chakravarti , Michael J Ackerman , Arne Pfeufer , Paul I W de Bakker , Christopher Newton-Cheh |
2014-08-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20930503 |
Cell Cycle Bernadette Aressy , Denis Jullien , Martine Cazales , Marlène Marcellin , Béatrix Bugler , Odile Burlet-Schiltz , Bernard Ducommun |
2010-09-15 | - |
| 20379614 |
Mol. Med. Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl |
2010-03-17 | - |
| 19615732 |
Defining the human deubiquitinating enzyme interaction landscape. Cell Mathew E Sowa , Eric J Bennett , Steven P Gygi , J Wade Harper |
2009-07-23 | - |
| 15060002 |
A genomic analysis of rat proteases and protease inhibitors. Genome Res. Xose S Puente , Carlos López-OtÃn |
2004-04-01 |
Gm10267,
Mug-ps1,
Mug2,
Gm4744,
Rhbdf2,
Prss48,
Casp16-ps,
Gm1330,
Ephx4,
Serpinb3d,
Gm14129,
Wfdc13,
Gm5415,
Gm9839,
Otud6a,
Gm5416,
Spink7,
Mug4-ps,
1700074P13Rik,
Klk1,
Prss27,
Bace2,
Mcpt8,
Klk10,
Oser1,
Psmb6,
Psma3,
Serpinb3,
LOC312273,
Smoc1,
Gfpt2,
Yod1,
Tmprss11b,
Pan2,
Ctsql2,
Abhd12b,
Prss58,
Tryx5,
Ggt6,
Mcpt8l3,
Mcpt4l1,
Mcpt1l3,
Klk4,
Klk5l,
Cpa5,
Tmprss11c,
Stfa2l1,
Stfa3l1,
Senp17,
Usp11,
Capn11,
Senp18,
Usp54,
Slpil3,
Wfdc6b,
Wfdc15a,
Wfdc12,
Wfdc9,
Slpil2,
Wfdc15b,
Spink14,
Spint5p,
Spink4,
Spink2,
Spink6,
Mug2,
Spink7,
Mcpt1l2,
Mcpt1l4,
Mcpt8l2,
Prss57,
Klk1c6,
Ece2,
Prss45,
Prss46,
C1rl,
Try10,
Psma3l,
CST9,
OVOS2,
SPINK13,
USP51,
USP50,
C3P1,
SPINK6,
OVOS,
SPINK14,
VTLGL1,
DDI1,
RHBDF2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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