| Type | Description |
|---|---|
| Definition | tripartite motif containing 23 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:19:00 | Data report that the Us11 protein targets TRIM23, which is a key regulator of autophagy-mediated antiviral defense mediated by TBK1. In virus-infected cells, the Us11 protein drastically reduces the formation of autophagosomes mediated by TRIM23 or TBK1. This autophagy-inhibitory effect is attributable to the binding of the Us11 protein to the ARF domain in TRIM23. | 31189704 |
| 2020-02-22 12:07:00 | Study found that TRIM23 was upregulated in lung adenocarcinoma (LUAD), and elevated TRIM23 expression was correlated with high expression of NF-kappaB, poor cellular differentiation, and adverse overall survival and disease-free survival. Furthermore, TRIM23 acted as an oncogene in LUAD and promoted cisplatin-resistance by regulating glucose metabolism. | 31677335 |
| 2020-01-18 12:55:00 | study identifies TRIM27 as a novel positive regulator of HCV replication | 30847745 |
| 2018-12-22 10:46:00 | TRIM23 may be associated with progression of gastric cancer | 30477642 |
| 2018-06-16 10:17:00 | work identifies the TRIM23-TBK1-p62 axis as a key component of selective autophagy and further reveals a role for K27-linked ubiquitination in GTPase-dependent TBK1 activation | 28871090 |
| Type | IDs |
|---|---|
| Synonymous | ARD1, ARFD1, RNF46 |
| Gene |
UniProtKB-ID:
TRI23_HUMAN
UniprotKB:
P36406
UniParc:
UPI0000125DB3,
UPI000002A3F1,
UPI000002A3F0
EMBL:
AF230397,
BC022510,
AF230398,
L04510,
AF230399
Ensembl:
ENSG00000113595
KO:
hsa:373
|
| Nucleutide sequences |
EMBL-CDS:
AAA35940.1,
AAG50178.1,
AAH22510.1,
AAG50176.1,
AAG50177.1
Ensembl_TRS:
ENST00000274327,
ENST00000381018,
ENST00000231524
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000274327,
ENSP00000370406,
ENSP00000231524
RefSeq:
NP_150231.1,
XP_016864933.1,
NP_150230.1,
NP_001647.1
|
| Others |
UniRef100:
UniRef100_P36406
UniRef90:
UniRef90_P36406
UniRef50:
UniRef50_P36406
UniGene:
Hs.792
CCDS:
CCDS43322.1,
CCDS3987.1,
CCDS3986.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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