| Type | Description |
|---|---|
| Definition | JunD proto-oncogene, AP-1 transcription factor subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | JUND-dependent up-regulation of HMOX1 is associated with cisplatin resistance in muscle-invasive bladder cancer. | 32240302 |
| 2020-12-26 13:11:00 | The mRNA encoding the JUND tumor suppressor detains nuclear RNA-binding proteins to assemble polysomes that are unaffected by mTOR. | 32312751 |
| 2020-10-03 12:58:00 | LncRNA LOXL1-AS1 is transcriptionally activated by JUND and contributes to osteoarthritis progression via targeting the miR-423-5p/KDM5C axis. | 32679142 |
| 2017-12-02 11:06:00 | Data indicate the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and suggest structural insight for therapeutic interventions targeting AP-1 proteins. | 28981703 |
| 2017-10-28 10:39:00 | In T cells, after serum deprivation HBZ induces the expression of Delta JunD isoform. Unlike JunD, Delta JunD induces proliferation and transformation of cells. HBZ bypasses translational control of JunD uORF and favors the expression of Delta JunD. The truncated isoform Delta JunD has a central role in the oncogenic process leading to adult T-cell leukemia . | 28260789 |
| Type | IDs |
|---|---|
| Synonymous | AP-1 |
| Gene |
UniProtKB-ID:
JUND_HUMAN
UniprotKB:
P17535
UniParc:
UPI00001AE750
EMBL:
X56681,
AK223630,
X51346,
CH471106,
EF044249
Ensembl:
ENSG00000130522
KO:
hsa:3727
|
| Nucleutide sequences |
EMBL-CDS:
CAA40010.1,
CAA35739.1,
ABJ53425.1,
EAW84684.1,
BAD97350.1
Ensembl_TRS:
ENST00000252818
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000252818
RefSeq:
NP_001273897.1,
NP_005345.3
|
| Others |
UniRef100:
UniRef100_P17535
UniRef90:
UniRef90_P17535
UniRef50:
UniRef50_P17535
UniGene:
Hs.2780
CCDS:
CCDS32959.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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