| Type | Description |
|---|---|
| Definition | jumonji and AT-rich interaction domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. | 33479123 |
| 2020-01-11 10:11:00 | show that DeltaN-JARID2 is a cleaved product of full-length JARID2 spanning the C-terminal conserved jumonji domains. JARID2 knockout in keratinocytes results in up-regulation of cell cycle genes and repression of many epidermal differentiation genes | 30573669 |
| 2019-08-03 10:45:00 | In this study, genetic mouse models and patient-derived xenografts demonstrated that JARID2 acts as a tumor suppressor in chronic myeloid disorders. | 30423295 |
| 2018-08-25 11:28:00 | rs2237126 in JARID2 is not significantly associated with childhood autism spectrum disorder or the severity of the disease in a Chinese Han population. | 29216786 |
| 2018-04-28 10:07:00 | bservations suggested that knockdown of JARID2 inhibited proliferation, migration and invasion in vitro through the inactivation of the PI3K/Akt signaling pathway. Therefore, JARID2 may represent a potential therapeutic target for the treatment of ovarian cancer. | 28765957 |
| Type | IDs |
|---|---|
| Synonymous | JMJ |
| Gene |
UniProtKB-ID:
JARD2_HUMAN
UniprotKB:
Q92833
UniParc:
UPI00019150D5,
UPI0000161C67,
UPI0001C48F9A
EMBL:
U57592,
AK299349,
BC046246,
CH471087,
BC046184,
AK292861,
AL021938,
AK303610,
AL136162
Ensembl:
ENSG00000008083
KO:
hsa:3720
|
| Nucleutide sequences |
EMBL-CDS:
AAC50822.1,
AAH46184.1,
BAF85550.1,
EAW55357.1,
AAH46246.1,
BAH13011.1,
BAH13996.1
Ensembl_TRS:
ENST00000341776,
ENST00000397311
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341280,
ENSP00000380478
RefSeq:
XP_011512881.1,
XP_024302192.1,
XP_016866324.1,
NP_004964.2,
NP_001253969.1,
XP_016866323.1,
XP_024302193.1,
XP_016866322.1
|
| Others |
UniRef100:
UniRef100_Q92833
UniRef90:
UniRef90_Q92833
UniRef50:
UniRef50_Q62315
UniGene:
Hs.269059
CCDS:
CCDS58996.1,
CCDS4533.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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