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37090 Ote

37090

Ote

Otefin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Otefin

研究结论

Date Results Publications
2021-02-02 13:28:00 Recruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication. 33168584
2020-07-18 12:43:00 loss of Bocksbeutel reduced Klarsicht localization to the nucleus and resulted in a disruption in nuclear separation. Loss of Otefin increased the transcription of Klarsicht and led to premature separation of nuclei and their positioning closer to the edge of the muscle. 31548202
2017-06-24 11:36:00 Ote is required autonomously for survival of male and female stem cell populations, as well as non-autonomously for maintenance of two somatic niches. Ote loss in ovary causes a decrease in cap cell number and altered signal transduction. Ote mutant males become prematurely sterile as they age. 27174470
2015-08-08 11:00:00 production of Bocks, but not dMAN1, rescued ote-/- sterility, demonstrating that Ote and Bocks are functional homologs 24700158
2013-09-07 11:44:00 We show that the primary defect in ote(-/-) GSCs is a block of differentiation, which ultimately leads to germ cell death. 23806619

名称对应

Type IDs
Synonymous CG5581, Dmel\CG5581, hal, ote, otefin
Gene
UniProtKB-ID: OTE_DROME
UniprotKB: P20240
UniParc: UPI00000076C7
EMBL: X17495, AY051940, AE013599
EnsemblGenome: FBgn0266420
KO: dme:Dmel_CG5581
Nucleutide sequences
EMBL-CDS: CAA35530.1, AAF57722.3, AAK93364.1
Gene_ORFName: CG5581
EnsemblGenome_TRS: FBtr0086768
Protein sequencees
EnsemblGenome_PRO: FBpp0085947
RefSeq: NP_476664.2
Others
UniRef100: UniRef100_P20240
UniRef90: UniRef90_P20240
UniRef50: UniRef50_P20240
UniGene: Dm.3658

全选

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研究热度

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