| Type | Description |
|---|---|
| Definition | temporal expression: early |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 10:10:00 | Vaccinia virus K1 inhibited acetylation of the RelA (p65) subunit of NF-kappaB, a nuclear event known to be required for NF-kappaB activation. | 27503790 |
| 2017-07-29 12:50:00 | Thus, vDeltaK1L is the first vaccinia virus construct reported that caused a muted innate immune gene expression profile and decreased immune cell infiltration in an intradermal model of infection yet still elicited protective immunity. | 28490586 |
| 2010-08-16 12:02:00 | Insertion of the K1L gene, which restores MVA replication in RK-13 cells, was not sufficient to extend MVA growth capacity to other mammalian cells. | 20627347 |
| 2010-04-12 11:37:00 | K1 residues on a continuous convex ANK repeat surface are critical for the host range function, suggesting that K1 functions through ligand interaction and does so with a novel ANK interaction surface. | 20089642 |
| 2010-02-15 11:05:00 | Viral K1L and C7L prevent eIF2alpha phosphorylation in vaccinia virus infection of human and murine cell lines. | 19846675 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
K1_VACCW,
B2BAD1_9POXV
UniprotKB:
P04297,
B2BAD1
UniParc:
UPI00000F39FA
EMBL:
EF051292,
M14319,
EF051286,
AY243312,
M27648,
D00382,
EF051291
KO:
vg:3707647
|
| Nucleutide sequences |
EMBL-CDS:
AAA69633.1,
BAA00286.1,
AAO89311.1,
AAA48299.1,
ABO09613.1,
ABO09614.1,
ABO09608.1
Gene_ORFName:
K1L
|
| Protein sequencees |
RefSeq:
YP_232914.1
|
| Others |
UniRef100:
UniRef100_P04297
UniRef90:
UniRef90_P04297
UniRef50:
UniRef50_P04297
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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