| Type | Description |
|---|---|
| Definition | temporal expression: early |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 10:37:00 | The data demonstrate that E3 promotes F1 expression by blocking activation of the double-stranded RNA-activated protein kinase R (PKR). | 29997208 |
| 2016-12-17 10:46:00 | The N terminus of F1L is not involved in apoptosis inhibition and may act as a regulatory element in other signaling pathways in a manner reminiscent of other unstructured regulatory elements commonly found in mammalian prosurvival Bcl-2 members including Bcl-xL and Mcl-1. | 27151220 |
| 2014-10-04 12:09:00 | Authors demonstrate that during vaccinia virus infection, engagement of Bim and Bak by F1L is crucial for subversion of host cell apoptosis. | 24850748 |
| 2013-07-20 11:58:00 | F1L protein has a role in virulence of vaccinia virus by inhibiting inflammasome activation | 23603272 |
| 2012-02-18 10:35:00 | Viral N1 and F1 do not act as direct cellular Bax inhibitors to prevent Bax-induced cell death. | 22013032 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1_VACCW
UniprotKB:
P24356
UniParc:
UPI0000186757
EMBL:
AY243312,
M34368
KO:
vg:3707497
|
| Nucleutide sequences |
EMBL-CDS:
AAO89319.1,
AAA48247.1
Gene_ORFName:
F1L
|
| Protein sequencees |
RefSeq:
YP_232922.1
|
| Others |
UniRef100:
UniRef100_P24356
UniRef90:
UniRef90_O57173
UniRef50:
UniRef50_O57173
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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