| Type | Description |
|---|---|
| Definition | Prophenoloxidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-21 10:31:00 | This study indicates that the mechanism of prophenoloxidase activation influences phenoloxidase (PO) activity. It also suggests that PO-induced different intermediates may affect the antibacterial activity during melanization due to their toxicity. | 29570828 |
| 2016-09-24 11:26:00 | Plant phenolics are detoxified by prophenoloxidase in the insect gut. | 26592948 |
| 2016-07-16 11:39:00 | PPO1 and PPO2 contribute to the bulk of melanization in the hemolymph, upon septic or clean injury. In contrast, PPO3, is expressed in lamellocytes and contributes to melanization during the encapsulation process. | 26437768 |
| 2016-02-06 10:55:00 | Genomic insertion of a PPO1(A480V) transgene phenocopies Black cells, proving that A480V is indeed the causal mutation of the historical Black cells phenotype. | 25543001 |
| 2015-06-20 11:52:00 | An important role for PPO1 and PPO2 in the survival to infection with Gram-positive bacteria and fungi, underlining the importance of melanization in insect host defense. | 24788090 |
| Type | IDs |
|---|---|
| Synonymous | A1, A[[1]], Bc, CG42639, CG5779, DmePPOA1, Dmel\CG42639, Dmel_CG5779, Dox-A1, DoxA1, Mox, PO, PO A1, PO54, PPO, PPO-1, PROPO-A1, Phox, ProPO, ProPO A1, ProPO54, ProPo, Propo, bc, i12, pro-A, pro-PO, pro-POA[[1]], proPO, proPO A[[1]], proPO-A1, proPO54 |
| Gene |
UniProtKB-ID:
Q7K2W6_DROME
UniprotKB:
Q7K2W6
UniParc:
UPI0000082B03
EMBL:
AY060617,
AE013599
EnsemblGenome:
FBgn0283437
KO:
dme:Dmel_CG42639
|
| Nucleutide sequences |
EMBL-CDS:
AAL28165.1,
AAF57775.1
Gene_ORFName:
CG42639,
Dmel_CG42639
EnsemblGenome_TRS:
FBtr0302291
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0291497
RefSeq:
NP_476812.1
|
| Others |
UniRef100:
UniRef100_Q7K2W6
UniRef90:
UniRef90_Q7K2W6
UniRef50:
UniRef50_Q7K2W6
UniGene:
Dm.3938
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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