| Type | Description |
|---|---|
| Definition | IL2 inducible T cell kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID-19 therapy. | 32640487 |
| 2020-08-13 17:10:00 | Loss of function in ITK can result in broad dysregulation of T-cell responses to oncogenic viruses, including beta-human papillomavirus and Epstein-Barr virus. | 30778533 |
| 2020-06-27 11:30:00 | The ITK SH3 and LCK SH3 domains can both competefor and simultaneously bind to adjacent binding sites on TSAD encompassing aa 242-268. | 31484725 |
| 2020-01-11 11:43:00 | ITK knockdown decreased IL-17A production in T cells primed under Th17 conditions and promoted Th1 differentiation. | 31022269 |
| 2019-11-02 10:50:00 | Specific ITKi had modest effects on apoptosis. | 30242208 |
| Type | IDs |
|---|---|
| Synonymous | EMT, LPFS1, LYK, PSCTK2 |
| Gene |
UniProtKB-ID:
ITK_HUMAN
UniprotKB:
Q08881
UniParc:
UPI000004CADA
EMBL:
CH471062,
BC109077,
BC109078,
D13720,
AK312846,
L10717,
S65186
Ensembl:
ENSG00000113263
KO:
hsa:3702
|
| Nucleutide sequences |
EMBL-CDS:
EAW61608.1,
BAG35699.1,
AAA36748.1,
AAB28072.2,
BAA02873.1,
AAI09078.1,
AAI09079.1
Ensembl_TRS:
ENST00000422843
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398655
RefSeq:
XP_016864932.1,
NP_005537.3
|
| Others |
UniRef100:
UniRef100_Q08881
UniRef90:
UniRef90_Q08881
UniRef50:
UniRef50_Q08881
UniGene:
Hs.558348
CCDS:
CCDS4336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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